A review on the neuroprotective effect of Nelumbo nucifera seed pod

Pn, Ruvanthika; Manikandan, S.

doi:10.26452/ijrps.v10i3.1469

Cited by 4 publications

(6 citation statements)

References 10 publications

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“…It has been demonstrated that some common food flavonoids can function as effective stabilisers of oil-in-water emulsions by adhering as water-insoluble particles to the oil droplets' surfaces, i.e., Pickering emulsions. A yellow colour formed after mixing 2 ml of orange peel extract with 1 ml of 2N sodium hydroxide suggests the presence of flavonoids [11].…”

Section: Test For Flavonoidsmentioning

confidence: 99%

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Organic pesticide from non-conventional natural resources

Bhattacharjee,

Kotame,

Mahajan

et al. 2023

IOP Conf. Ser.: Mater. Sci. Eng.

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The new varieties of organic pesticides and their application as a substitute for chemical pesticides are the main topics of this paper. Due to the residue left on the vegetables, fruits, etc. which we consume on a daily basis, many of the contemporary, chemical pesticides being utilised today are reducing the soil fertility and negatively damaging human health. Study has shown that natural oils also work as pesticides but the emulsion of oil and water is big task so for that We need chemical based emulsifier so to avoid chemicals we are studying on various fruits and vegetable extracts which can be used as emulsifiers. According to the data of year 2020-21 Maharashtra leads with the 13243 MT of usage of pesticides. Orange peel extract contain chemicals such as saponins and flavonoids, which have the property of emulsifier for the emulsion of oil and water. After studying various papers, we found that orange peel extract can definitely work as emulsifier for oil and water emulsion. In this paper we got to know the presence of saponins with the help of froth test (test for saponins), test for flavonoids and the UV-Vis absorbance spectrum of the orange peel. In this we got the yield of orange peel extract using two different solvents. Paper tells us about the different analysis performed with the help of the parameters obtained for finding the presence of emulsifying properties present in orange peel.

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Section: Test For Flavonoidsmentioning

confidence: 99%

“…Three to four drops of ferric chloride at 1% were then added. After that, a blue-black or brownish-green color was observed [11]. 4.3.5.…”

Section: Test Formentioning

confidence: 99%

Organic pesticide from non-conventional natural resources

Bhattacharjee,

Kotame,

Mahajan

et al. 2023

IOP Conf. Ser.: Mater. Sci. Eng.

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“…A significant difference was considered b/w group when p<0.05. All analyses were done with GraphPad Prism 8.0.2 software [9,10,11,24] .…”

Section: 10statistical Analysismentioning

confidence: 99%

Effect of Nelumbo nucifera rhizome extract in haloperidol induced Parkinson rat model

2022

pnr

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In the present investigation, we tried to evaluate the anti-Parkinson activity of NN rhizome in haloperidol-induced Parkinson in mice.Material and Method: Ethanolic extract was obtained from the rhizome of Nelumbo nucifera (NN). The solvent extractions were subjected to preliminary phytochemical screening. Neural degeneration was induced in a group (2, 3,4,5) by ip. Administration of Haloperidol at 1mg/kg in an animal. The standard drug L-Dopa 30 mg/kg ip. was ingested to group 3 animals before 30 of haloperidol challenge for 14 days. EENN at 250 and 500 mg/kg daily orally were given to G4, and G5 respectively before 30 min of haloperidol challenge for 14 days. A behavioral parameter was recorded on days 7 and 13 for bar test, days 8 and 14 for the rotarod test, and days 6 and 11 for locomotor activity. All statistical analyses were done with one-way and two-way ANOVA followed by Tukey's multiple comparison tests.Result: EENN significantly (p<0.0001) improves the experimental rat's muscle coordination, locomotor, and catatonic behavior. Conclusion: Nelumbo nucifera extract produces maximum (dose-dependent) significant action on Parkinson (dopaminergic neuron) in haloperidol-induced Parkinson in an animal.

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“…12 The extract of N. nucifera also reported activity against neurodegenerative diseases. 13 Various benzyl tetrahydroisoquinolne (BTIQ) and aporphine (i.e., nuciferine and nornuciferine), alkaloids found in lotus flower and leaves 14 displayed many neuropharmacological activities. The alkaloid fraction of lotus leaveshave also showed prominent anxiolytic, sedative and hypnotic potential by binding with GABA receptor and stimulating the monoaminergic receptor system.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Potential of Nelumbo nucifera (Sacred Lotus) in CNS Disorders

Mitra

Raihan

Rahman

et al. 2022

Dhaka Univ. J. Pharm. Sci

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Nelumbo nucifera (sacred lotus), locally known as Poddo, has been used as food and traditional remedy in Ayurvedic system in India and Traditional Chinese Medicine for a wide range of diseases. During past two decades, there are numerous scientific studies and general reviews have been published on its phytochemistry and pharmacology. However, in this paper, we aim to make a survey on neuropharmacological effects, as well as psychoactivities, of N. nucifera, identifying the active constituents and their proposed mechanism of actions which has not been systematically documented in the literature. Several online databases, including Google Scholar, PubMed, Web of Science, Science Direct, and Scopus were employed to conduct this survey. Previous studies have demonstrated that N. nucifera has potential neuropharmacological effects in various test systems, including in vivo animal models and in vitro cultured cells or enzymes through various mechanistic pathways, including 5-HT2A receptor blockade, GABAergic system, regulating the NCAM and GAP-43 expression levels, regulating for skolinstimulated cAMP production, and many more. Our survey showed that many alkaloids isolated from N. nucifera demonstrated antidepressant, sedative-hypnotic, anxiolytic, analgesia-potentiating action, anticonvulsant, antipsychotic, and memory enhancer activities. Although many studies have showed potential neurotherapeutic benefits of this plant and many of its constituents, but the focus of research towards clinical trial in human is rather very limited. Dhaka Univ. J. Pharm. Sci. 20(3): 347-358, 2022 (June) Centennial Special Issue

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A review on the neuroprotective effect of Nelumbo nucifera seed pod

Cited by 4 publications

References 10 publications

Organic pesticide from non-conventional natural resources

Organic pesticide from non-conventional natural resources

Effect of Nelumbo nucifera rhizome extract in haloperidol induced Parkinson rat model

Therapeutic Potential of Nelumbo nucifera (Sacred Lotus) in CNS Disorders

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