A review on toxoplasmosis in humans and animals from Egypt

Abbas, Ibrahim; Villena, Isabelle

doi:10.1017/s0031182019001367

Cited by 38 publications

(35 citation statements)

References 88 publications

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“…Based on the number of live births annually in these 6 centres, 4-8 congenitally infected children were born per 10 000 births but details are lacking (El Bissati et al, 2018). There are many unconfirmed reports of congenital toxoplasmosis and spontaneous abortion associated with toxoplasmosis in Egypt; these were recently reviewed by Abbas et al (2020). Most of these reports are based on serological results on single samples from pregnant women, and detection of DNA in the placenta.…”

Section: Africamentioning

confidence: 99%

Congenital toxoplasmosis in humans: an update of worldwide rate of congenital infections

et al. 2021

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Section: Africamentioning

confidence: 99%

Congenital toxoplasmosis in humans: an update of worldwide rate of congenital infections

et al. 2021

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“…Several studies have also shown the effects of close contact with the meat of infected animals, consumption of raw meat, vegetable, and contaminated water [1,13,56,[61][62][63][64]. Further, the infection rate has been reported to be influenced by education level, socioeconomic status, age groups, and local religious beliefs of the community [1,7,58,62,65,66]. PLOS NEGLECTED TROPICAL DISEASES…”

Section: The Pooled Prevalence Of Seropositivity For Toxoplasma Gondimentioning

confidence: 99%

Potential risk factors associated with seropositivity for Toxoplasma gondii among pregnant women and HIV infected individuals in Ethiopia: A systematic review and meta-analysis

et al. 2020

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Background Toxoplasma gondii is an obligate intracellular and neurotropic apicomplexan protozoan parasite infecting almost all warm-blooded vertebrates including humans. To date in Ethiopia, no systematic study has been investigated on the overall effects of potential risk factors associated with seropositivity for Toxoplasma gondii among pregnant women and HIV infected individuals. We intended to determine the potential risk factors (PRFs) associated with seropositivity for Toxoplasma gondii from published data among pregnant women and HIV infected individuals of Ethiopia. Methodology An systematic review of the previous reports was made. We searched PubMed, Science Direct, African Journals Online, and Google Scholar for studies with no restriction on the year of publication. All references were screened independently in duplicate and were included if they presented data on at least two risk factors. Meta-analysis using the random or fixed-effects model was made to calculate the overall effects for each exposure. Results Of the 216 records identified, twenty-four reports met our eligibility criteria, with a total of 6003 individuals (4356 pregnant women and 1647 HIV infected individuals). The pooled prevalences of anti-Toxoplasma gondii antibodies were found at 72.5% (95% CI: 58.7% - 83.1%) in pregnant women and 85.7% (95% CI: 76.3% - 91.8%) in HIV infected individuals. A significant overall effect of anti-Toxoplasma gondii seropositivity among pregnant women (p < 0.05) was witnessed with age, abortion history, contact with cats, cat ownership, having knowledge about toxoplasmosis, being a housewife and having unsafe water source. Age, cat ownership, and raw meat consumption were also shown a significant effect (p < 0.05) to anti-Toxoplasma gondii seropositivity among HIV infected individuals. Conclusions This review showed gaps and drawbacks in the earlier studies that are useful to keep in mind to design accurate investigations in the future. The pooled prevalence of anti-Toxoplasma gondii antibodies was found to be higher among pregnant women and HIV infected individuals. This suggests that thousands of immunocompromised individuals (pregnant women and HIV infected patients) are at risk of toxoplasmosis due to the sociocultural and living standards of the communities of Ethiopia. Appropriate preventive measures are needed to reduce the exposure to Toxoplasma gondii infection. Further studies to investigate important risk factors are recommended to support the development of more cost-effective preventive strategies.

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“…Toxoplasma gondii ( T. gondii ) is the cause of toxoplasmosis, which is a highly neglected disease that can be life-threatening in both humans and animals worldwide [ 1 , 2 ]. The disease can affect all mammals and birds, and the latter also play a significant role as a cause of zoonotic infection [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

A Review on the Prevalence of Toxoplasma gondii in Humans and Animals Reported in Malaysia from 2008–2018

Wana

Moklas

Watanabe

et al. 2020

IJERPH

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Toxoplasmosis is a disease caused by the protozoan parasite Toxoplasma gondii (T. gondii). Human toxoplasmosis seroprevalence in Malaysia has increased since it was first reported in 1973 as shown in previous reviews of 1991 and 2007. However, over a decade since the last review, comprehensive data on toxoplasmosis in Malaysia is lacking. This work aimed at reviewing articles on toxoplasmosis research in Malaysia in order to identify the research gaps, create public awareness, and efforts made so far and proffer management options on the disease. The present review examines the available published research articles from 2008 to 2018 related to toxoplasmosis research conducted in Malaysia. The articles reviewed were retrieved from nine credible databases such as Web of Science, Google Scholar, ScienceDirect, PubMed, Scopus, Springer, Wiley online library, Ovid, and Cochrane using the keywords; Malaysia, toxoplasmosis, Toxoplasma gondii, toxoplasma encephalitis, seroprevalence, human immunodeficiency virus (HIV) patients, pregnant women, genotype strain, anti-toxoplasma antibodies, felines, and vaccine. The data highlighted seropositive cases from healthy community members in Pangkor Island (59.7%) and among migrant workers (57.4%) at alarming rates, as well as 42.5% in pregnant women. Data on animal seroprevalence were limited and there was no information on cats as the definitive host. Genetic characterization of Toxoplasma gondii from HIV patients; pregnant women, and domestic cats is lacking. This present review on toxoplasmosis is beneficial to researchers, health workers, animal health professionals, and policymakers. Therefore, attention is required to educate and enlighten health workers and the general public about the risk factors associated with T. gondii infection in Malaysia.

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A review on toxoplasmosis in humans and animals from Egypt

Cited by 38 publications

References 88 publications

Congenital toxoplasmosis in humans: an update of worldwide rate of congenital infections

Congenital toxoplasmosis in humans: an update of worldwide rate of congenital infections

Potential risk factors associated with seropositivity for Toxoplasma gondii among pregnant women and HIV infected individuals in Ethiopia: A systematic review and meta-analysis

A Review on the Prevalence of Toxoplasma gondii in Humans and Animals Reported in Malaysia from 2008–2018

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