“…22,23 As a result, other natural polymers such as chitosan, hyaluronic acid, silk broin, and synthetic polymers such as polylactic acid, polycaprolactone, and polyvinyl alcohol are also commonly used in biological materials. [24][25][26] In particular, the Nacetylglucosamine moiety of chitosan is similar to the glycosaminoglycan in bone extracellular matrix (ECM), which can attract growth factors and proteins to induce new bone regeneration. 27 In addition, the positive charge of chitosan can improve cell adhesion and diffusion to alter cell behavior.…”