A Review Study on the Prevalence of Helicobacter Pylori Infection in Laryngeal Carcinoma

Abstract

Introduction: Malignant tumors of the larynx make up 2 to 5 percent of cancers each year. Infections can cause about 15% of the world's cancers with great environmental variations. One of the cases that have been investigated for its etiologic role in laryngeal carcinoma is Helicobacter pylori infection. Object: The aim of this review study is to investigate the available paper that evaluate association between Helicobacter pylori infection and laryngeal carcinoma. Material and method: Extensive research was conducted on some medical and microbiology database of life sciences such as Pub Med, EMBASE, MEDLINE, LILACS database, global independent network of Cochrane. By referencing these databases, a comprehensive literature review was carried out through combining numerous recent studies in terms of laryngeal carcinoma, Helicobacter pylori infection, epidemiology and management in accordance with many related articles published from 2000 to 2020 which could cover this area of recommendations. Conclusions: The Helicobacter pylori infection can affect the larynx cancer. Some studies investigated this relation. In this study we evaluated these studies. Different effect of Helicobacter pylori on larynx cancer was detected in these paper, some study showed strong effect of this infection in larynx cancer while another study reported any relation. So further studies needed to evaluate this relation although the Helicobacter pylori infection is main reason of many disease and its prevention and treatment is necessary.