A risk score to predict in-hospital mortality in patients with pancreatic cancer.

Zhang, Shuang Yin; Jiang, Jimmy Jinghua; El‐Rayes, Bassel F.

doi:10.1200/jco.2015.33.15_suppl.e15256

Cited by 2 publications

(1 citation statement)

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“…6 Electrolyte disorders in cancer patients have important prognostic implications; 7 they appear to be the strongest predictors of mortality along with coagulopathy, and renal failure, increasing mortality in hospitalized patients with some types of cancer. 8 These disorders are said to increase morbidity and mortality by cancer and decrease the quality of life. 9 Critically ill cancer patients, patients having renal diseases, patients taking medications or in chemotherapy, and endocrine disorders associated with Syndrome of in appropriate Anti-Diuretic Hormone secretion (SIADH) were prone to electrolyte disorders.…”

Section: Factors Influencing the Occurrence Of Electrolyte Disorders In Cancer Patientsmentioning

confidence: 99%

Factors influencing the occurrence of electrolyte disorders in cancer patients

et al. 2021

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Objective: The objective of this study was to determine the magnitude of electrolyte disorders and influencing factors among cancer patients in Southwest Ethiopia. Methods: Facility-based cross-sectional study was conducted in Jimma Medical Center (JMC). Eighty-four cancer patients admitted to JMC were recruited for this study. A structured questionnaire and serum electrolyte measurements were used for data collection. Bivariate and multiple logistic regression was employed to determine the association between electrolyte disorders and associated factors among admitted cancer patients. P value ⩽ 0.05 was used as a cut point to declare statistical significance. Result: The overall prevalence of electrolyte disorders was 60.7%. The presence or absence of comorbid diseases, age, body mass index (BMI), nutritional status, and current prescribed medication use were associated with electrolyte disorders. Younger patients had lower odds for electrolyte disorders (odds ratio (OR) = 0.128 (P value = 0.05) and OR = 0.08 (P value = 0.033)) for the first and the second quartile, respectively. Underweight patients had a threefold likelihood to develop electrolyte disorders (OR = 3.13 (P value = 0.043)) than having normal BMI. Compared with those in need of nutritional intervention, patients not in need of nutritional intervention had lower odds for the disorders (OR = 0.109 (P value = 0.006)). Medication had increased the likelihood of electrolyte disorders by 5.5 times than with no medication (P value = 0.023). Those who had comorbid disease had 10 times likely to develop electrolyte disorders than those who did not have comorbid diseases (P value = 0.004). Conclusion: Electrolyte disorders were prevalent in cancer patients. Age, BMI, nutritional condition, comorbid disease, and prescribed drugs were the predictors of electrolyte disorders in cancer patients. Authors recommend routine screening of electrolyte disorders in cancer patients and special emphasis on controlling and managing risk factors.

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Section: Factors Influencing the Occurrence Of Electrolyte Disorders In Cancer Patientsmentioning

confidence: 99%

Factors influencing the occurrence of electrolyte disorders in cancer patients

et al. 2021

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Study of the clinical effectiveness of an accompanying rehabilitation complex with nutritional and infusional electrolyte support in patients with gastric cancer receiving immunotherapy

Koneva,

Mochalova,

Ogorodnikov

et al. 2024

Physiotherapist

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Abstract. Immunotherapeutic drugs have radically changed the concept of therapeutic algorithms for systemic treatment of cancer patients. Immunotherapy has been associated with increased overall survival for a significant portion of the cancer patient population. This also means that the number of patients who require long-term support aimed at maintaining quality of life, functional status and social activity is growing. Rehabilitation, aimed at the individual needs of each person, is an integral part of recovery support. Objective. We assessed individual needs for rehabilitation measures, including analysis of nutritional and functional status, as well as the spectrum of electrolyte disturbances over time during immunotherapeutic treatment in cancer patients with advanced unresectable gastric cancer. Material and methods. The study included 21 patients with advanced gastric cancer, the average age of the participants was 62.2 years. Eighteen patients were treated with nivolumab + FOLFOX, 3 patients with pembrolizumab + FOLFOX. All patients underwent a course of physical therapy and nutritional support in the form of sipping between meals (nutrient mixtures) from preventive to therapeutic regimens. All patients were surveyed about nutritional risk and quality of life (EORTC QLQ C30) before starting treatment and after completing the immunotherapy line. Results. The quality of life of patients according to a dynamic survey (EORTC QLQ 30) was significantly better after six months of treatment. Despite the lack of significant significance of changes in the nutritional status of patients, a positive trend was noted — all patients with NRS3 improved their scores to NRS2 or NRS1. The feasibility of studying electrolyte status and individual electrolyte support as a necessary component of complex rehabilitation was also noted. The study is planned to be continued in a randomized trial on a larger sample, expanding the objective measures studied to include disease-free and overall survival, objective response to treatment, and duration of response to treatment.

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A risk score to predict in-hospital mortality in patients with pancreatic cancer.

Cited by 2 publications

References 0 publications

Factors influencing the occurrence of electrolyte disorders in cancer patients

Factors influencing the occurrence of electrolyte disorders in cancer patients

Study of the clinical effectiveness of an accompanying rehabilitation complex with nutritional and infusional electrolyte support in patients with gastric cancer receiving immunotherapy

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