1980
DOI: 10.1038/284470a0
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A role for collagen in the pathogenesis of muscular dystrophy?

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Cited by 125 publications
(54 citation statements)
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References 17 publications
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“…The phenomenon may be viewed irreversible derangement of muscle tissue organization (2,5,12). Fibrosis hinders nutritional support of myofibers, particularly in the advanced stages when they become physically isolated from blood supply (2).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The phenomenon may be viewed irreversible derangement of muscle tissue organization (2,5,12). Fibrosis hinders nutritional support of myofibers, particularly in the advanced stages when they become physically isolated from blood supply (2).…”
Section: Discussionmentioning
confidence: 99%
“…Myofiber degeneration is followed by muscle fibrosis, predominantly composed of type HI collagen and involving the endomysium and perimysium (12). Fibrosis may be evident at the early stage and progresses with the disease.…”
Section: Introductionmentioning
confidence: 99%
“…4a, lane t), a doublet of relatively well-resolved bands with apparent molecular weights of 130,000 and 140,000 were precipitated together with another polypeptide with an apparent molecular weight of 255,000. Because its distribution in frozen-sectioned muscle was similar to that described for type III collagen by Duance et al (12), further experiments were undertaken to determine whether or not antigen-39 might also be collagenous. Conditioned medium, containing either [35S]methionine-or [3H]proline-and [3H]glycine-labeled secreted products, was treated with purified bacterial collagenase before immunoprecipitation.…”
Section: Antigen-31--lamininmentioning
confidence: 99%
“…A Cinemetria é um ramo da biomecânica que busca medir os parâmetros cinemáticos do movimento, ou seja, investigar a posição, deslocamento, velocidade e aceleração de um ou diferentes segmentos de interesse (AMADIO et al, 1999 Estudos sobre a presença e proporção das fibras colágenas nas distrofias musculares têm encontrado variações nestes dois aspectos, em relação aos tipos I, III e IV (DUANCE et al, 1980;STEPHENS et al, 1982;RAMPOLDI et al, 1986;HANTAI et al, 1995;PASSERINI et al, 2002). Ainda que os achados de cada autor, em relação ao tipo de colágeno alterado na DMD sejam variáveis, existe um consenso de que os tipos I, III e IV, dentre todos os outros já descritos merecem atenção no estudo da fibrose e adaptação tecidual.…”
Section: Avaliação Biomecânicaunclassified
“…A fim de melhor entender a localização da fibrose no músculo distrófico e as adaptações teciduais na presença da fisioterapia, utilizamos a análise imuno-histoquímica dos colágenos do tipo I, III e IV, uma vez que são apontados por diferentes estudos como quantitativamente aumentados na DMD (DUANCE et al, 1980;HANTAI et al, 1995;HUEBNER et al, 2008).…”
Section: Força De Reação Do Solo X Velocidadeunclassified