2009
DOI: 10.1016/j.mehy.2008.09.040
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A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome

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Cited by 111 publications
(81 citation statements)
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“…Naked viral and bacterial DNA fragments firmly bound to insoluble aluminum salts can be carried into tissue macrophages through phagocytosis to initiate a series of DNA-related immune reactions [31][32][33][34]. Intramuscular injection of free HPV-16 L1 plasmid DNA in BALB/C mice without adjuvant has been known to induce a strong CD8 T cell response [35], indicating that under certain conditions non-replicating HPV L1 gene DNA can activate the immune system.…”
Section: Discussionmentioning
confidence: 99%
“…Naked viral and bacterial DNA fragments firmly bound to insoluble aluminum salts can be carried into tissue macrophages through phagocytosis to initiate a series of DNA-related immune reactions [31][32][33][34]. Intramuscular injection of free HPV-16 L1 plasmid DNA in BALB/C mice without adjuvant has been known to induce a strong CD8 T cell response [35], indicating that under certain conditions non-replicating HPV L1 gene DNA can activate the immune system.…”
Section: Discussionmentioning
confidence: 99%
“…Whereas numerous environmental factors have been linked to the origin of GWS, the role of the adjuvant aluminium hydroxide associated to the multiple vaccines that Western army soldiers underwent during the months before their departure to the Persian Gulf War has come under increasing scrutiny (95) . Recently, GWS, together with other syndromes linked to previous exposure to an adjuvant, including macrophagic myofascitis syndrome (MMS) (96) , siliconosis and other post-vaccination adverse effects, have been included in the autoimmune/ inflammatory syndrome induced by adjuvants, the ASIA syndrome (97) .…”
Section: Aluminium and The Gulf War Syndrome (Gws)mentioning
confidence: 99%
“…A 2002 study of the VAERS database related to Hepatitis B vaccine confirmed a significant number of adverse reactions in adults [97]. A case study published in 2009 described an adult's profound adverse reaction to multiple vaccinations containing aluminum, resulting in aluminum hydroxide deposits accumulating in macrophages in muscle cells, along with debilitating muscle pain and weakness associated with chronic fatigue syndrome and macrophagic myofasciitis [98].…”
Section: Other Related Workmentioning
confidence: 99%