A scalable database of organ doses for common diagnostic fluoroscopy examinations of children: procedures of current practice at the University of Florida

Abstract

Of all the medical imaging modalities that utilize ionizing radiation, fluoroscopy proves to be the most difficult to assess values of patient organ dose owing to the dynamic and patient-specific nature of the irradiation geometry and its associated x-ray beam characteristics. With the introduction of the radiation dose structured report (RDSR) in the mid-2000s, however, computational tools have been developed to extract patient and procedure-specific data for each irradiation event of the study, and when coupled to a computational phantom of the patient, values of skin and internal organ dose may be assessed. Unfortunately, many legacy and even current diagnostic fluoroscopy units do not have RDSR reporting capabilities, thus limiting these dosimetry reporting advances. Nevertheless, knowledge of patient organ doses for patient care, as well as for radiation epidemiology studies, remains a research and regulatory priority. In this study, we created procedural outlines which document all radiation exposure information required for organ dose assessment, akin to a reference RDSR, for six common diagnostic fluoroscopy procedures performed at the University of Florida (UF) Shands Pediatric Hospital. These procedures include the voiding cystourethrogram, the gastrostomy-tube placement, the lower gastrointestinal study, the rehabilitation swallow, the upper gastrointestinal study, and the upper gastrointestinal study with follow through. These procedural outlines were used to develop an extensive database of organ doses for the 162-member UF/NCI (National Cancer Institute) library of pediatric hybrid phantoms, with each member varying combinations of sex, height, and weight. The organ dose assessment accounts for the varying x-ray fields, fluoroscopy time, relative concentration of x-ray contrast in the organs, and changes in the fluoroscope output due to patient size. Furthermore, we are also reporting organ doses normalized to total fluoroscopy time, reference point air kerma, and kerma-area product, effectively providing procedure dose coefficients. The extensive organ dose library produced in this study may be used prospectively for patient organ dose reporting or retrospectively in epidemiological studies of radiation-associated health risks.

Associated radiation exposure from medical imaging and excess lifetime risk of developing cancer in pediatric patients with pulmonary hypertension

“…Doses for nuclear medicine and radiographs were estimated using a detailed dose map generated for an unrelated National Institutes of Health funded study 15 . Radiation doses for fluoroscopy exams (swallow evaluations, upper and lower gastrointestinal [GI] studies, and upper GI studies with small bowel follow through) were estimated using a detailed exam specific estimate created for an unrelated study quantifying cancer risk in children 16 . If patients underwent less common fluoroscopy studies, doses were not included.…”

“… 15 Radiation doses for fluoroscopy exams (swallow evaluations, upper and lower gastrointestinal [GI] studies, and upper GI studies with small bowel follow through) were estimated using a detailed exam specific estimate created for an unrelated study quantifying cancer risk in children. 16 If patients underwent less common fluoroscopy studies, doses were not included. The UCSF Institutional Review Board (IRB) approved this study and provided a waiver for individual informed consent (IRB Number 21‐34589).…”