A Selective Synthesis of (E)-Vinylsilanes by Cationic Rhodium Complex-Catalyzed Hydrosilylation of 1-Alkynes and Tandem Hydrosilylation/Isomerization Reaction of Propargylic Alcohols to .beta.-Silyl Ketones

Gold‐Film‐Catalysed Hydrosilylation of Alkynes by Microwave‐Assisted, Continuous‐Flow Organic Synthesis (MACOS)

“…Column chromatography purifications were carried out by using the flash technique on silica gel 60 (200-400 mesh). 1 H NMR spectroscopy was run by using a Bruker Advance 400 MHz instrument and all spectra were calibrated to d = 7.26 ppm for the signal from the residual proton of the deuterated chloroform solvent; 13 C NMR spectra were calibrated to the middle carbon signal of the triplet for deuterated chloroform (d = 77.00 ppm).…”

“…Purification by flash chromatography (20 % dichloromethane in pentane) afforded 94 mg of 3 e (68 % yield including minor isomers). [13] (E)-5-Chloro-1-(triphenylsilyl)-1-pentene (3 f): 5-Chloro-1-pentyne and triphenylsilane were reacted by following the general hydrosilylation procedure and 750 mL of the crude reaction mixture were collected. Purification by flash chromatography (12 % dichloromethane in hexane) afforded 189.7 mg of 3 f (70 % yield including minor isomers).…”

“…Purification by flash chromatography (20 % ethyl acetate in hexane) afforded 191.0 mg of 3 n (78 % yield including minor isomers). 1 H NMR (400 MHz, CDCl 3 ): d = 7.58-7.63 (m, 6 H), 7.38-7.51 (m, 9 H), 6.38 (dt, J = 18.5, 1.5 Hz, 1 H), 6.18 (dt, J = 18.5, 6.0 Hz, 1 H), 2.41-2.46 (m, 2 H), 2.37 (t, J = 7.3 Hz, 2 H), 1.87 ppm (t, J = 7.3 Hz, 2 H); 13 C NMR (100 MHz, CDCl 3 ): d = 150.0, 136.0, 134.6, 129.8, 127.9, 126.5, 119.6, 35.5, 24.3, 16.6 ppm; spectra matched those found in the literature. [12] (E)-1-(Triethylsilyl)-1-buten-3-ol (3 o): 3-Butyne-2-ol and triethylsilane were reacted by following the general hydrosilylation procedure and 900 mL of the crude reaction mixture were collected.…”

Effect of the synthetic method of Pt/MgO in the hydrosilylation of phenylacetylene

“…The important catalytic activity of platinum supported on carbon, silicates and silica in the hydrosilylation of ethylene, butadiene, acetylene and allyl chloride with trichlorosilane has been reported. 2 There are several examples that have been studied to reach this goal and more expensive catalysts have been employed for this purpose [6][7][8][9] .…”

New Organogermanium Substrates for Palladium-Catalyzed Cross-Coupling Reactions. Application of Organogermanes towards the Synthesis of Carbon-5 Modified Uridine Analogues

“…and 116c with 0.5 equivalent of (TMS) 3 SiH in the presence of Wilkinson's catalyst 179 efficiently effected the isomerization to give the corresponding (E)-silanes 117a (78%) and 117c (89%). Extended heating (54 h) of 116b in the presence of (TMS) 3 SiH/RhCl(PPh 3 ) 3 /NaI resulted in the quantitative conversion of 116b into 117b.…”