In view of the high cost of integrated energy dispatching in the power grid, which affects the economic benefits of power enterprises, an optimization method of integrated energy dispatching in the power grid based on multivariate big data is designed. The method comprises the following steps of: firstly, extract integrated data characteristics of power grid dispatching, and integrate power grid energy dispatching data; secondly, process the power grid energy dispatching data by using multiple big data, and reduce a dispatching convergence error; and finally, construct a power grid integrated energy dispatching optimization model, improve the net profit of power grid dispatching, and further realize the optimal dispatching of the demand of a supply side and a demand side of a power grid. By the way of comparative experiments, it is verified that the net profit of this method is higher. The economic benefit is higher, and it can be applied to real life.