A sensor for detection of carcinoembryonic antigen based on the polyaniline-Au nanoparticles and gap-based interdigitated electrode

Li, Xueqin; Yu, Mingxin; Chen, Zhichun; Lin, Xianfu; Wu, Qi

doi:10.1016/j.snb.2016.08.101

Cited by 58 publications

(19 citation statements)

References 46 publications

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“…Polyaniline (PANi) is one of the well-known conducting polymers that has been widely used in numerous applications including supercapacitors, 2-4 batteries, 5 chemical and biological sensors, 6,7 electrical conductors, 8 and in anti-static coatings. 9 However, PANi has some disadvantages: for example, it has low dispersibility and solubility in most solvents and low electron transfer rates and conductivity in solutions with a higher pH, which have limited its performance in biosensors and electrical devices.…”

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confidence: 99%

Polyaniline-modified nanocellulose prepared from Semantan bamboo by chemical polymerization: preparation and characterization

et al. 2017

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Crystalline nanocellulose was prepared from Semantan bamboo (Gigantochloa scortechinii) via acid hydrolysis and was used to synthesize a nanocomposite of polyaniline/crystalline nanocellulose (PANi/CNC) via in situ oxidative polymerization of aniline in the presence of crystalline nanocellulose. The electrochemical properties of the nanocomposite were studied using a modified PANi/CNC electrode via cyclic voltammetry, and higher current response was observed for the PANi/CNC-modified electrode compared to that for the modified electrode with PANi. The results obtained from EIS displayed lower value of R ct for the PANi/CNCmodified electrode, indicating that the incorporation of CNC into the PANi structure could enhance the electron transfer rate. The characteristic peaks of PANi and CNC were observed in the FTIR spectra of the nanocomposite, indicating the incorporation of CNC inside the nanocomposite structure. Moreover, in the XRD diffractogram, lower crystallinity was observed at the 2 theta values of 22.6 and 16.1 for PANi/CNC compared to that for pure CNC. The FESEM images showed high porosity of the nanostructure with no phase separation, revealing the homogenous polymerization of the monomer on the surface of the crystalline cellulose. Aggregation of PANi particles was observed with the increasing aniline concentration.

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confidence: 99%

Polyaniline-modified nanocellulose prepared from Semantan bamboo by chemical polymerization: preparation and characterization

et al. 2017

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“…The homogeneous distribution of Au NPs on PANFs resulted in a strong interaction between Au NPs and PANFs which enhanced the electroactivity of PANFs and the electrocatalytic activity of Au NPs for the oxidation and determination of H 2 O 2 . Recently, Chen et al . have prepared an electrochemical immunosensor based on PANI‐AuNPs and gap‐based interdigitated electrode (IDEs) for detection of carcinoembryonic antigen (CEA).…”

Section: Conducing Polymer Nanocomposites‐based Non‐enzymatic Electrodesmentioning

confidence: 99%

Recent Progress in the Development of Conducting Polymer‐Based Nanocomposites for Electrochemical Biosensors Applications: A Mini‐Review

Naseri

Fotouhi

Ehsani

2018

The Chemical Record

132

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Among various immobilizing materials, conductive polymer-based nanocomposites have been widely applied to fabricate the biosensors, because of their outstanding properties such as excellent electrocatalytic activity, high conductivity, and strong adsorptive ability compared to conventional conductive polymers. Electrochemical biosensors have played a significant role in delivering the diagnostic information and therapy monitoring in a rapid, simple, and low cost portable device. This paper reviews the recent developments in conductive polymer-based nanocomposites and their applications in electrochemical biosensors. The article starts with a general and concise comparison between the properties of conducting polymers and conducting polymer nanocomposites. Next, the current applications of conductive polymer-based nanocomposites of some important conducting polymers such as PANI, PPy, and PEDOT in enzymatic and nonenzymatic electrochemical biosensors are overviewed. This review article covers an 8-year period beginning in 2010.

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“…Serious medical conditions such as cancers have also been included in the medical applications of microelectrode‐based biosensing. For example, Li et al . have recently reported the development of a carcinoembryonic antigen sensor based on a polyaniline‐gold nanoparticle and gap‐based interdigitated electrode.…”

Section: Disease Biomarker Detection At Structurally Small Electrodesmentioning

confidence: 99%

Recent Advances in Biosensing for Neurotransmitters and Disease Biomarkers using Microelectrodes

2017

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This Minireview focuses on recent advances in the applications of microelectrodes to detect and monitor targeted analytes in bioelectrochemical processes. Notably, these processes are electrochemically driven reactions that involve the detection of targets from the biological realm. Wide‐ranging applications of electrochemical sensors have been reported in the last few decades in various research fields, owing to favorable attributes such as high selectivity and sensitivity, rapid analysis, simplicity, easy fabrication, and cost effectiveness. Accordingly, in this Minireview, we explore recent advances in bioelectrochemistry based on small detection probes or structures modified for a variety of analytes, exploiting multi‐approach advantages of enhanced electrochemical detection surface or targeted analyte pursuit. The target analytes included in this Minireview are neurotransmitters and disease biomarkers detected using enzymatic and non‐enzymatic electrode modifications.

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A sensor for detection of carcinoembryonic antigen based on the polyaniline-Au nanoparticles and gap-based interdigitated electrode

Cited by 58 publications

References 46 publications

Polyaniline-modified nanocellulose prepared from Semantan bamboo by chemical polymerization: preparation and characterization

Polyaniline-modified nanocellulose prepared from Semantan bamboo by chemical polymerization: preparation and characterization

Recent Progress in the Development of Conducting Polymer‐Based Nanocomposites for Electrochemical Biosensors Applications: A Mini‐Review

Recent Advances in Biosensing for Neurotransmitters and Disease Biomarkers using Microelectrodes

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