A short and efficient asymmetric synthesis of (1S,2R)-(+)-5-methoxy-1-methyl-2-(di-n-propylamino)tetralin hydrochloride (UH-232)

Highly diastereo- and enantioselective copper-catalyzed methylboration of 1,2-dihydroquinolines and 2H-chromenes

“…20 Significantly, after oxidation and protection using a methanesulfonyl or tosyl group with excellent diastereo- and enantioselectivities, product 4i was used to prepare a kind of ubiquitin-specific inhibitor according to the literature. 21…”