A signal-on electrochemical aptasensor for sensitive detection of human epididymis protein 4 based on functionalized metal–organic framework/ketjen black nanocomposite

Hu, Rongqin; Mu, Zhaode; Gong, Feng; Qing, Min; Yuan, Yao; Bai, Lijuan

doi:10.1007/s10853-023-08627-9

J Mater Sci

2023

DOI: 10.1007/s10853-023-08627-9

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A signal-on electrochemical aptasensor for sensitive detection of human epididymis protein 4 based on functionalized metal–organic framework/ketjen black nanocomposite

Rongqin Hu

Zhaode Mu

Feng Gong³

et al.

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Cited by 4 publications

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Sensitive and Cost‐Effective Tools in the Detection of Ovarian Cancer Biomarkers

Elhami,

Mobed,

Soleimany

et al. 2024

Analytical Science Advances

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Women diagnosed with late‐stage ovarian cancer suffer a very high rate of mortality. Accordingly, it is imperative to detect and diagnose the disease as early as possible in its development. Achievement of this aim implies relatively large‐scale screening of women at an age of clinical significance through assay of biomarkers for disease present in blood or serum. Biosensor detection offers an attractive technology for the automated detection of such species. Among several biomarkers that have been identified that are present in patients with ovarian cancer, the only one that is commonly tested for in clinical use is cancer antigen 125, which is considered to be a poor biomarker for the disease. Here, we describe several biosensors that developed in the past decade for the detection of ovarian cancer biomarkers such as CA125, human epididymis protein 4 (HE4) and apolipoprotein A1. The challenges presented by the fabrication of biosensor devices for detecting ovarian cancer and the limited number of biosensors developed for this purpose are discussed.

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Sensitive and Cost‐Effective Tools in the Detection of Ovarian Cancer Biomarkers

Elhami,

Mobed,

Soleimany

et al. 2024

Analytical Science Advances

View full text Add to dashboard Cite

show abstract

Recent advances in ovarian cancer diagnosis using 2D nanomaterials-based electrochemical biosensors: a review

Lavanya,

Sankar,

Sindhuja

et al. 2024

J Mater Sci

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Recent advances in electrochemical MOF-based aptasensors for cancer biomarker detection: A review

Wu,

Zhang,

et al. 2024

Microchemical Journal

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A signal-on electrochemical aptasensor for sensitive detection of human epididymis protein 4 based on functionalized metal–organic framework/ketjen black nanocomposite

Cited by 4 publications

References 36 publications

Sensitive and Cost‐Effective Tools in the Detection of Ovarian Cancer Biomarkers

Sensitive and Cost‐Effective Tools in the Detection of Ovarian Cancer Biomarkers

Recent advances in ovarian cancer diagnosis using 2D nanomaterials-based electrochemical biosensors: a review

Recent advances in electrochemical MOF-based aptasensors for cancer biomarker detection: A review

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