2018
DOI: 10.1039/c8ay00713f
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A simple colorimetric analytical assay using gold nanoparticles for specific detection of tetracycline in environmental water samples

Abstract: In this work, an aptamer-based colorimetric method for the detection of tetracycline (TC) was established by employing gold nanoparticles (AuNPs) as the colorimetric probe.

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Cited by 42 publications
(14 citation statements)
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“…As a result, the degree of AuNP aggregation is a direct reflection of the target concentration and can be observed by the red to purple-blue color change in the AuNP solution. Based on the similar strategies, the label-free colorimetric detection of various targets, including proteins [77,78,79,80], small organic molecules [81,82,83], and ions, such as silver (I) [84], cadmium (II) [85] and potassium (I) [86], has been explored extensively.…”
Section: Aggregation-based Colorimetric Assaysmentioning
confidence: 99%
“…As a result, the degree of AuNP aggregation is a direct reflection of the target concentration and can be observed by the red to purple-blue color change in the AuNP solution. Based on the similar strategies, the label-free colorimetric detection of various targets, including proteins [77,78,79,80], small organic molecules [81,82,83], and ions, such as silver (I) [84], cadmium (II) [85] and potassium (I) [86], has been explored extensively.…”
Section: Aggregation-based Colorimetric Assaysmentioning
confidence: 99%
“…This method was reported for the detection of Ag + , [59] kanamycin, [60,61] chloramphenicol, [62,63] 17β-estradiol, [64] melamine [65,66] and tetracycline. [67][68][69] To test this mechanism, we quantitatively measured the amount of desorbed aptamers in the presence of various target molecules using a few FAM-labeled aptamers (Figure 3). [23] If an aptamer is specifically desorbed, higher fluorescence enhancement would be observed with its target than with other molecules.…”
Section: Figure 2 (A)mentioning
confidence: 99%
“…This method was also used for detecting various antibiotics such as kanamycin, [60,61] tetracycline, [67][68][69] chloramphenicol, [62,63] sulfadimethoxine, [47,48] biological analytes like 17β-estradiol, [64] ATP, [50,57,58] environmental and food contaminants like bisphenol A, [49] and melamine (M), [65,66] and illicit drugs including cocaine (O), [54,80] and methamphetamine (P). [51] These ions and molecules have vastly different structures and properties, leading to different interactions with AuNPs.…”
Section: Examples Of Targets For Aptamer-based Detectionmentioning
confidence: 99%
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“…In the field of food detection, they have an extremely broad usage for the detection of small molecules, and they rival antibodies to some degree. Aptamers have been used to detect small molecules including patulin [ 7 ], ochratoxin [ 8 ], ractopamine [ 9 ] chloramphenicol [ 10 ], clenbuterol [ 11 ], aflatoxin B1 [ 12 ], and tetracycline [ 13 ]. The ochratoxin aptamer [ 14 , 15 , 16 ] is the most commonly used aptamer, also known as the star aptamer.…”
Section: Introductionmentioning
confidence: 99%