A simple fluorescent strategy for liver capillary labeling with carbon quantum dot-lectin nanoprobe

An, Chang-Zhi; Li, Chao-Qing; Song, Lai-Bo; He, Yan-Fei; Chen, W.; Liu, Bo; Zhao, Yuan‐Di

doi:10.1039/d1an02364k

Cited by 3 publications

(2 citation statements)

References 42 publications

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“…After atomic doping, the surface groups of CQDs are more abundant and have better water solubility [ 28 ], fluorescence [ 29 ], and antibacterial properties [ 30 ]. CQDs are commonly used in fields such as drug delivery [ 31 , 32 ], tissue engineering [ 33 , 34 ], fluorescence labeling [ 35 , 36 ], and food preservation [ 37 , 38 ].…”

Section: Introductionmentioning

confidence: 99%

Construction Strategy and Mechanism of a Novel Wood Preservative with Excellent Antifungal Effects

Wang,

Hao

et al. 2024

Molecules

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Wood is a naturally porous material prone to microbial erosion and degradation in outdoor environments. Therefore, the development of an environmentally friendly wood preservative with excellent antibacterial effects and low toxicity is urgently needed. In this study, nitrogen-doped carbon quantum dots (N-CQDs) with excellent antifungal performance and fluorescent properties were synthesized using a one-step hydrothermal method with chitosan quaternary ammonium salt (HACC) as the raw material. The fluorescence characteristics of N-CQD preservatives can help track their position and distribution in wood. The minimum inhibitory concentration (MIC) of N-CQDs is 1.8 mg/mL, which was nearly 22 times lower than that of HACC (40.0 mg/mL) in the PDA medium. The decay resistance test demonstrated that wood treated with N-CQDs showed a considerably reduced decay degree and its mass loss rate decreased from 46 ± 0.5% to 3.8 ± 0.5%. Biological transmission electron microscopy revealed that N-CQDs effectively destroyed fungal cell structures, thereby hindering the growth of Coriolus versicolor. N-CQDs synthesized using the one-step hydrothermal method can be used as an efficient wood preservative that can effectively improve the utilization and service life of wood.

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Section: Introductionmentioning

confidence: 99%

Construction Strategy and Mechanism of a Novel Wood Preservative with Excellent Antifungal Effects

Wang,

Hao

et al. 2024

Molecules

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“…On the other hand, since their inception in 2004, carbon nanodots (CNDs) have been recognized as a strong contender to replace the extremely dangerous metallic semiconductor class of quantum dots [3]. This is partly because the characteristics of carbon quantum dots are widely acknowledged to include their nanoscale size, roughly flat or spherical morphologies, great water solubility, broad absorption in the UV-visible light spectrum, and vibrant fluorescence [4]. CNDs have an amorphous or nanocrystalline center, mainly sp 2 carbon, graphite grid spacing, and outside oxygenic functional groups, allowing for water solubility and subsequent complexation.…”

Section: Introductionmentioning

confidence: 99%

Carbon-Based Fluorescent Nano-Biosensors for the Detection of Cell-Free Circulating MicroRNAs

et al. 2023

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Currently, non-communicable diseases (NCDs) have emerged as potential risks for humans due to adopting a sedentary lifestyle and inaccurate diagnoses. The early detection of NCDs using point-of-care technologies significantly decreases the burden and will be poised to transform clinical intervention and healthcare provision. An imbalance in the levels of circulating cell-free microRNAs (ccf-miRNA) has manifested in NCDs, which are passively released into the bloodstream or actively produced from cells, improving the efficacy of disease screening and providing enormous sensing potential. The effective sensing of ccf-miRNA continues to be a significant technical challenge, even though sophisticated equipment is needed to analyze readouts and expression patterns. Nanomaterials have come to light as a potential solution as they provide significant advantages over other widely used diagnostic techniques to measure miRNAs. Particularly, CNDs-based fluorescence nano-biosensors are of great interest. Owing to the excellent fluorescence characteristics of CNDs, developing such sensors for ccf-microRNAs has been much more accessible. Here, we have critically examined recent advancements in fluorescence-based CNDs biosensors, including tools and techniques used for manufacturing these biosensors. Green synthesis methods for scaling up high-quality, fluorescent CNDs from a natural source are discussed. The various surface modifications that help attach biomolecules to CNDs utilizing covalent conjugation techniques for multiple applications, including self-assembly, sensing, and imaging, are analyzed. The current review will be of particular interest to researchers interested in fluorescence-based biosensors, materials chemistry, nanomedicine, and related fields, as we focus on CNDs-based nano-biosensors for ccf-miRNAs detection applications in the medical field.

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Dissecting the neurovascular unit in physiology and Alzheimer's disease: Functions, imaging tools and genetic mouse models

Li¹,

Li²,

Wei³

et al. 2023

Neurobiology of Disease

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A simple fluorescent strategy for liver capillary labeling with carbon quantum dot-lectin nanoprobe

Abstract: Taking the hepatic sinusoid (HS) as the main delivery area of liver nutrient and metabolic waste, recognizing its structure is important for the deep understanding of liver function. In this...

Cited by 3 publications

References 42 publications

Construction Strategy and Mechanism of a Novel Wood Preservative with Excellent Antifungal Effects

Construction Strategy and Mechanism of a Novel Wood Preservative with Excellent Antifungal Effects

Carbon-Based Fluorescent Nano-Biosensors for the Detection of Cell-Free Circulating MicroRNAs

Dissecting the neurovascular unit in physiology and Alzheimer's disease: Functions, imaging tools and genetic mouse models

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