A simple intensity noise reduction technique for optical low-coherence reflectometry

Sorin, Wayne V.; Baney, D.M.

doi:10.1109/68.180591

Cited by 108 publications

(46 citation statements)

References 6 publications

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“…Of course an increase in the sample beam power will increase the SNR when imaging biological tissue, but the reference power must not be allowed to increase into the photon bunching regime. While our results confirm those of Sorin and Baney [17], we will use somewhat different language to describe this phenomenon theoretically.…”

Section: Fundamental Photon Noise Limitationssupporting

confidence: 79%

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An optical coherence microscope for 3-dimensional imaging in developmental biology

Hoeling¹,

Fernandez²,

Haskell³

et al. 2000

Opt. Express

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An optical coherence microscope (OCM) has been designed and constructed to acquire 3-dimensional images of highly scattering biological tissue. Volume-rendering software is used to enhance 3-D visualization of the data sets. Lateral resolution of the OCM is 5 µm (FWHM), and the depth resolution is 10 µm (FWHM) in tissue. The design trade-offs for a 3-D OCM are discussed, and the fundamental photon noise limitation is measured and compared with theory. A rotating 3-D image of a frog embryo is presented to illustrate the capabilities of the instrument.

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Section: Fundamental Photon Noise Limitationssupporting

confidence: 79%

“…This is only partially true. Like Sorin and Baney [17], we have found that the SNR in our OCM is improved by attenuating the power in the reference beam. Typical SLD sources operate with powers and coherence times that lead to photon noise dominated by Bose-Einstein photon bunching.…”

Section: Fundamental Photon Noise Limitationssupporting

confidence: 74%

An optical coherence microscope for 3-dimensional imaging in developmental biology

Hoeling¹,

Fernandez²,

Haskell³

et al. 2000

Opt. Express

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show abstract

“…where the sample arm power was assumed to be much smaller than the reference arm power, 9 with s r1d 2 being the sum of the readout noise and the dark noise and t coh ͑2 ln 2͞p͒ 1͞2 l 0 2 ͞cdl being the coherence time, where c is the speed of light. 10 The optimal signal-to-noise ratio (SNR) performance is achieved when shot noise dominates both readout noise and RIN.…”

mentioning

confidence: 99%

“…10 The optimal signal-to-noise ratio (SNR) performance is achieved when shot noise dominates both readout noise and RIN. 9 Shot noise dominates RIN when their ratio is larger than one, i.e., E v ͞hP ref t coh . 1.…”

mentioning

confidence: 99%

In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography

et al. 2004

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An ultrahigh-speed spectral domain optical coherence tomography (SD-OCT) system is presented that achieves acquisition rates of 29,300 depth profiles͞s. The sensitivity of SD-OCT and time domain OCT (TD-OCT) are experimentally compared, demonstrating a 21.7-dB improvement of SD-OCT over TD-OCT. In vivo images of the human retina are presented, demonstrating the ability to acquire high-quality structural images with an axial resolution of 6 mm at ultrahigh speed and with an ocular exposure level of less than 600 mW.

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“…To correct dispersion differences between the reference and sample arms, we used a dispersion compensation prism pair (AFS-SF10, Thorlabs Inc.) in the reference arm. We used a neutral density (ND) filter in the reference arm to reduce the source intensity noise [31]. Recombined light from the reference and sample arms was incident onto the balanced detector (PDB110A, Thorlabs Inc.) via the circulator and coupler.…”

Section: Fd/ss-oct Setup and Data Processingmentioning

confidence: 99%

Fourier Domain Optical Coherence Tomography for Retinal Imaging with 800-nm Swept Source: Real-time Resampling in k-domain

Lee¹,

Song²,

Kim³

et al. 2011

Journal of the Optical Society of Korea

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In this study, we demonstrated Fourier-domain/swept-source optical coherence tomography (FD/SS-OCT) at a center wavelength of 800 nm for in vivo human retinal imaging. A wavelength-swept source was constructed with a semiconductor optical amplifier, a fiber Fabry-Perot tunable filter, isolators, and a fiber coupler in a ring cavity. Our swept source produced a laser output with a tuning range of 42 nm (779 to 821 nm) and an average power of 3.9 mW. The wavelength-swept speed in this configuration with bidirectionality is 2,000 axial scans per second. In addition, we suggested a modified zero-crossing method to achieve equal sample spacing in the wavenumber (k) domain and to increase the image depth range. FD/SS-OCT has a sensitivity of ~89.7 dB and an axial resolution of 10.4 μm in air. When a retinal image with 2,000 A-lines/frame is obtained, an acquisition speed of 2.0 fps is achieved.

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A simple intensity noise reduction technique for optical low-coherence reflectometry

Cited by 108 publications

References 6 publications

An optical coherence microscope for 3-dimensional imaging in developmental biology

An optical coherence microscope for 3-dimensional imaging in developmental biology

In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography

Fourier Domain Optical Coherence Tomography for Retinal Imaging with 800-nm Swept Source: Real-time Resampling in k-domain

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