A simple method of determining e-aminocaproic acid (EACA) in urine

ε-Aminocaproic Acid (EACA)

“…In the case of a presence of other reacting compounds in the mixture, classical chromatographic or HPLC methods of separation are used (46)(47)(48)(49). Antifibrinolytic activity of EACA is determined after a deproteinization of plasma, urine and tissue homogenate with the use of trichloroacetic acid (TCA) or perchloric acid (HClO 4 ) (50,51). The purpose of this procedure is a removal of plasminogen, plasminogen activators, inhibitors of activators and antiplasmin.…”