A simple near-patient test for nicotine and its metabolites in urine to assess smoking habit

Cope, Graham; Nayyar, Pamela; Holder, Roger; Gibbons, John; Bunce, Roger

doi:10.1016/s0009-8981(96)06417-0

Cited by 42 publications

(34 citation statements)

References 23 publications

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“…This was assessed for cotinine using a colorimetric assay 'SmokeScreen Test'. 121 Results were categorised into nonsmokers and evidence that the patient was still smoking.…”

Section: Cotinine-validated Smoking Cessationmentioning

confidence: 99%

The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence

Jolly¹,

Taylor²,

Gy³

et al. 2007

Health Technol Assess

174

262

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“…This was assessed for cotinine using a colorimetric assay 'SmokeScreen Test'. 121 Results were categorised into nonsmokers and evidence that the patient was still smoking.…”

Section: Cotinine-validated Smoking Cessationmentioning

confidence: 99%

The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence

Jolly¹,

Taylor²,

Gy³

et al. 2007

Health Technol Assess

174

262

View full text Add to dashboard Cite

show abstract

“…3 The aim of the current study was to use the new test, referred to as IsoScreen, to audit adherence to anti-tuberculous drug therapy and compare this with the established method of visual detection of RIF in orange-stained urine.…”

Section: Introductionmentioning

confidence: 99%

Point-of-care test to monitor adherence to anti-tuberculous treatment

Whitfield

Cope

2004

Ann Clin Biochem

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Background In the fight against the global tuberculosis epidemic, it is essential to ensure that patients adhere to the treatment prescribed. As the treatment is given for a minimum of 6 months it is common for patients not to take their drugs regularly. Strategies are therefore needed to assess adherence to treatment. One established method is to examine the patient's urine for the presence of drug metabolites. A rapid point-of-care test would overcome some of the drawbacks associated with currently available methods.

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“…Its incorporation into a simple-to-use, inexpensive, disposable format has allowed the test to be carried out in situations outside of the laboratory. 2 The effect of passive smoking on salivary antioxidant status was unexpected. However, tobacco smoke, yielding a high concentration of free radicals, could have a local effect on the buccal cavity.…”

Section: Resultsmentioning

confidence: 99%

“…Chloramine-T (Sigma) was isolated in a washer-like annulus, with a space between two tightly ®tting plastic discs which formed a seal on top of the chamber. 2 In use, 2 mL of unprocessed urine were aspirated by the syringe, which was inserted into the barrel, breaking the seal and dispensing the chloramine-T into the reaction chamber. The urine was injected onto the reagents, which dissolved, thereby starting the reaction.…”

Section: Methodsmentioning

confidence: 99%

“…To facilitate this feedback we have developed a near-patient test to monitor active smoking using a colorimetric assay to measure nicotine and its metabolites incorporated into a disposable plastic enclosure. 2 We have used this to monitor active smoking in pregnancy and cardiovascular disease. We recently modi®ed the reagents to improve sensitivity to detect nicotine metabolites in saliva in order to develop a chair-side test to monitor smoking in dental practice.…”

mentioning

confidence: 99%

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Simple colorimetric test to quantify exposure to environmental tobacco smoke: occupational health study

Cope

Nayyar²,

Wilkinson³

et al. 2000

Ann Clin Biochem

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A simple near-patient test for nicotine and its metabolites in urine to assess smoking habit

Cited by 42 publications

References 23 publications

The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence

The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence

Point-of-care test to monitor adherence to anti-tuberculous treatment

Simple colorimetric test to quantify exposure to environmental tobacco smoke: occupational health study

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