A simple UV-photolysis digestion method for the determination of fluoride in fluorine-containing drugs by ion-selective electrode and spectrophotometry techniques

Krishna, M. Bala; Rao, Shodhan; Murthy, Varanasi S N; Karunasagar, D.

doi:10.1039/c2ay05718b

Cited by 15 publications

(3 citation statements)

References 36 publications

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“…Despite the relatively widespread use of spectrophotometry for fluorine determination in pharmaceutical and health care products [35,44], few applications of these methods could be found for biological samples (Table 2). For this kind of matrix, procedures for fluorine determination are relatively simple and based on low-cost instrumentation.…”

Section: Spectrophotometric Methodsmentioning

confidence: 99%

Analytical methods for the determination of halogens in bioanalytical sciences: a review

et al. 2013

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Fluorine, chlorine, bromine, and iodine have been studied in biological samples and other related matrices owing to the need to understand the biochemical effects in living organisms. In this review, the works published in last 20 years are covered, and the main topics related to sample preparation methods and analytical techniques commonly used for fluorine, chlorine, bromine, and iodine determination in biological samples, food, drugs, and plants used as food or with medical applications are discussed. The commonest sample preparation methods, as extraction and decomposition using combustion and pyrohydrolysis, are reviewed, as well as spectrometric and electroanalytical techniques, spectrophotometry, total reflection X-ray fluorescence, neutron activation analysis, and separation systems using chromatography and electrophoresis. On this aspect, the main analytical challenges and drawbacks are highlighted. A discussion related to the availability of certified reference materials for evaluation of accuracy is also included, as well as a discussion of the official methods used as references for the determination of halogens in the samples covered in this review.

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Section: Spectrophotometric Methodsmentioning

confidence: 99%

Analytical methods for the determination of halogens in bioanalytical sciences: a review

et al. 2013

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“…This means it migrates through membranes much more readily, and hence the fluorinated molecule has a higher bioavailability. 53…”

Section: Substituent Effect On Lipophilicity and Retention Factorsmentioning

confidence: 99%

B3LYP Study of 3-hydroxynaphthalene-2-carboxanilide para-derivatives

Michalík

Poliak

Lukeš

2018

ACSi

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A systematic DFT investigation of 3-hydroxy-N-phenylnaphthalene-2-carboxamide and its sixteen para-derivatives is presented. The structural analysis showed that the energetically preferred conformation of all derivatives is practically planar and it is stabilised via intramolecular hydrogen bonds occurring between (C)O ... H(3)O atomic pairs. The quantum chemically evaluated partition coefficients logarithms correlate well with Quantitative Structure-Activity Relationship models as well as with experimentally determined isocratic retention factors logarithm. Theoretical gas-phase proton affinities of amido and hydroxyl group together with selected partial atomic charges reflect the terminal phenyl substitution effect. These quantities are linearly dependent on the in vitro activity against the Mycobacterium Kansasii. Obtained linear correlation functions based on quantum chemically evaluated microscopic properties and selected experimental data may serve as the effective tool in modern drug design for the description of substitution effect.

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“…The difficulties of ISE include electrode drift, time consumption for equilibration and dissolution of the lanthanum fluoride membrane crystal 6 . Most traditional spectroscopic techniques, which study interactions between matter and radiated energy 7 , have similar detection ranges down to the microgram level ( Additional file 1 : Supplementary Table 1 ).…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Sensing of Fluoride in Cellular System

Jiao¹,

Zhu²,

Chen³

et al. 2015

Theranostics

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Fluoride ions have the important roles in a lot of physiological activities related with biological and medical system, such as water fluoridation, caries treatment, and bone disease treatment. Great efforts have been made to develop new methods and strategies for F- detection in the past decades. Traditional methods for the detection of F- including ion chromatography, ion-selective electrodes, and spectroscopic techniques have the limitations in the biomedicine research. The fluorescent probes for F- are very promising that overcome some drawbacks of traditional fluoride detection methods. These probes exhibit high selectivity, high sensitivity as well as quick response to the detection of fluoride anions. The review commences with a brief description of photophysical mechanisms for fluorescent probes for fluoride, including photo induced electron transfer (PET), intramolecular charge transfer (ICT), fluorescence resonance energy transfer (FRET), and excited-state intramolecular proton transfer (ESIPT). Followed by a discussion about common dyes for fluorescent fluoride probes, such as anthracene, naphalimide, pyrene, BODIPY, fluorescein, rhodamine, resorufin, coumarin, cyanine, and near-infrared (NIR) dyes. We divide the fluorescent probes for fluoride in cellular application systems into nine groups, for example, type of hydrogen bonds, type of cleavage of Si-O bonds, type of Si-O bond cleavage and cylization reactions, etc. We also review the recent reported carriers in the delivery of fluorescent fluoride probes. Seventy-four typical fluorescent fluoride probes are listed and compared in detail, including quantum yield, reaction medium, excitation and emission wavelengths, linear detection range, selectivity for F-, mechanism, and analytical applications. Finally, we discuss the future challenges of the application of fluorescent fluoride probes in cellular system and in vivo. We wish that more and more excellent fluorescent fluoride probes will be developed and applied in the biomedicine field in the future.

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A simple UV-photolysis digestion method for the determination of fluoride in fluorine-containing drugs by ion-selective electrode and spectrophotometry techniques

Cited by 15 publications

References 36 publications

Analytical methods for the determination of halogens in bioanalytical sciences: a review

Analytical methods for the determination of halogens in bioanalytical sciences: a review

B3LYP Study of 3-hydroxynaphthalene-2-carboxanilide para-derivatives

Fluorescent Sensing of Fluoride in Cellular System

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