A Simple Way to Improve Immunoreactivity of Prostate Needle Biopsies Fixed in Bouin’s Solution to AMACR

Ortiz-Rey, J.A.; Miguel-Fraile, Pilar San; María, C. Gómez de; Lama, Silvia Huri de; Sánchez, Manuel Marín

doi:10.1097/pai.0b013e31826b56cd

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“…1,2,8,9 Immunohistochemical analysis is useful, as seminal vesicle would show expression of high molecular weight cytokeratin in basal cells and would be negative for AMACR, in opposition to pros-tate adenocarcinoma. 10 Prostate-specific antigen and prostate-specific acid phosphatase are not useful for the differential diagnosis as they are not specific of prostate epithelium and may label seminal vesicle/ejaculatory duct tissue. 10 Prostate-specific antigen and prostate-specific acid phosphatase are not useful for the differential diagnosis as they are not specific of prostate epithelium and may label seminal vesicle/ejaculatory duct tissue.…”

Section: To the Editormentioning

confidence: 99%