A simplified strategy to reduce the desorbent consumption and equipment installed in a three-zone simulated moving bed process for the separation of glucose and fructose

Tangpromphan, Preuk; Budman, Hector; Jaree, Attasak

doi:10.1016/j.cep.2018.02.001

Cited by 6 publications

(1 citation statement)

References 47 publications

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“…Yao et al [49], Pangpromphan et al [50,51] and Nam et al [52] investigated the application of three-zone SMB in the food separation process. Yao et al constructed the first asynchronous three-zone SMB for the separation of vanillin and syringaldehyde.…”

Section: Applications For Three-zone Smbmentioning

confidence: 99%

Research Progress on the Typical Variants of Simulated Moving Bed: From the Established Processes to the Advanced Technologies

et al. 2023

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Simulated moving bed (SMB) chromatography is a highly efficient adsorption-based separation technology with various industrial applications. At present, its application has been successfully extended to the biochemical and pharmaceutical industrial sectors. SMB possesses the advantages of high product purity and yield, large feed treatment capacity, and simple process control due to the continuous operation mode and the efficient separation mechanism, particularly for difficult separation. Moreover, SMB performs well, particularly for multi-component separation or complicated systems’ purification processes in which each component exhibits similar properties and low resolution. With the development of the economy and technology, SMB technology needs to be improved and optimized to enhance its performance and deal with more complex separation tasks. This paper summarizes the typical variants or modifications of the SMB process through three aspects: zone variant, gradient variant, and feed or operation variant. The corresponding modification principles, operating modes, advantages, limitations, and practical application areas of each variant were comprehensively investigated. Finally, the application prospect and development direction were summarized, which could provide valuable recommendations and guidance for future research in the SMB area.

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