A single crystal bent Laue monochromator for coronary angiography

Suortti, P.; Thomlinson, W.; Chapman, Dean; Gmür, Nicholas F.; Siddons, D. P.; Schulze, C.

doi:10.1016/0168-9002(93)91114-3

Cited by 56 publications

(37 citation statements)

References 15 publications

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“…3). The monochromator is based on a single bent Laue silicon crystal [12], which creates two monochromatic beams characterized by a bandwidth equal to 200 eV in the case of both iodine and gadolinium. The two monochromatic beams (one above and one below the K edge separated by a splitter) are deflected upwards, at a mean angle of 6.84 at 33.169 keV and 4.51 at 50.239 keV according Bragg's law.…”

Section: Instrumentationmentioning

confidence: 99%

Feasibility of synchrotron radiation computed tomography on rats bearing glioma after iodine or gadolinium injection

et al. 2000

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The purpose of this work was to demonstrate the feasibility of a new imaging technique called synchrotron radiation computed tomography (SRCT). This technique leads to a direct assessment of the in vivo concentration of an iodine- or gadolinium-labeled compound. Rats bearing C6 glioma were imaged by MRI prior to the SRCT experiment. The SRCT experiments were performed after a 1.3 g I/kg (n = 5) or a 0.4 g Gd/kg (n = 5) injection. Finally, brains were sampled for histology. The SRCT images exhibited contrast enhancement at the tumor location. Ten minutes after injection, iodine and gadolinium tissular concentrations were equal to 0.80 ( +/- 0.40) mg/cm3 and 0.50 ( +/- 0.10) mg/cm3, respectively in the peripheral area of the tumor (respective background value: 0.20 +/- 0.02 to 0.10 +/- 0.01). Correlation to MRI and histology revealed that the contrast uptake occurred in the most vascularized area of the tumor. The present study summarizes the feasibility of in vivo SRCT to obtain quantitative information about iodine and gadolinium-labeled compounds. Beyond brain tumor pathology, the SRCT appears as a complementary approach to MRI and CT, for studying iodine- and gadolinium-labeled compounds by the direct achievement of the tissular concentration value in the tissue.

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Section: Instrumentationmentioning

confidence: 99%

Feasibility of synchrotron radiation computed tomography on rats bearing glioma after iodine or gadolinium injection

et al. 2000

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“…The differential imaging technique is based on the use of two images, exposed with x-ray radiation both above and below the K-edge of the contrast agent, which can be subtracted to enhance the contrast in the parts of the image containing the contrast agent. Differential imaging for coronary angiography has already been tested with synchrotron x-radiation, using iodine (K-edge at 33.2 keV) as a contrast agent (6,7). Gadolinium (K-edge at 50.2 keV) is another clinically approved contrast agent where Gd Ka-and Ta Ka-radiation from a laser-produced source can be used for the double exposure, above and below the K-edge of Gd.…”

Section: Introductionmentioning

confidence: 99%

X-Ray Crystal Spectroscopy of Sub-picosecond Laser-Produced Plasmas beyond 50 keV*1

Hölzer

1997

Journal of X-Ray Science and Technology

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The interaction of a sub-picosecond (sub-ps) laser with a high-Z target produces a hard x-ray continuum, but to our knowledge no high-resolution study of the line emission is known. We present here crystal spectroscopy as a tool for the observation of energetic line x-radiation from a sub-ps laser-produced plasma. Reflection properties of flat and bent crystals for x-ray spectroscopy are analyzed theoretically for both the Bragg and the Laue geometries and optimized for a crystal spectroscopy of hard (ú50 keV) x-radiation. The crystal setup is optimized for spectroscopic applications with regard to high throughput and spectral resolution. The characteristic tantalum Ka,b-and La,b-line emissions from a sub-ps laser-produced plasma is observed for the first time. A resolving power of about 450 is achieved which is much higher than that for comparable absorption filter techniques (E/DE É 15). ᭧ 1997 Academic Press

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“…(2) is like Eq. (4) in [1] but accounts for the inequality of the rotation of the diffracting planes and that of the surface normal along the ray paths for general φ. If q Q, there will be a thickness-dependent broadening of the intended image at q.…”

Section: Crystal Designmentioning

confidence: 99%

“…The crystals have been manufactured by Crystal Scientific (UK) Ltd (Alnwick, United Kingdom) and have been installed in a crystal cage assembly manufactured by FMB Oxford Ltd (Oxford, United Kingdom). The remaining parameters to be optimized were the asymmetry angle of the reflections and the crystal bending radius, which are determined by the two types of focusing in meridionally bent Laue crystals [1,2].…”

Section: Crystal Designmentioning

confidence: 99%

Three-energy focusing Laue monochromator for the diamond light source x-ray pair distribution function beamline I15-1

Sutter¹,

Chater²,

Hillman³

et al. 2016

AIP Conference Proceedings

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Abstract. The I15-1 beamline, the new side station to I15 at the Diamond Light Source, will be dedicated to the collection of atomic pair distribution function data. A Laue monochromator will be used consisting of three silicon crystals diffracting X-rays at a common Bragg angle of 2.83°. The crystals use the (1 1 1), (2 2 0), and (3 1 1) planes to select 40, 65, and 76 keV X-rays, respectively, and will be bent meridionally to horizontally focus the selected X-rays onto the sample. All crystals will be cut to the same optimized asymmetry angle in order to eliminate image broadening from the crystal thickness. Finite element calculations show that the thermal distortion of the crystals will affect the image size and bandpass.

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A single crystal bent Laue monochromator for coronary angiography

Cited by 56 publications

References 15 publications

Feasibility of synchrotron radiation computed tomography on rats bearing glioma after iodine or gadolinium injection

Feasibility of synchrotron radiation computed tomography on rats bearing glioma after iodine or gadolinium injection

X-Ray Crystal Spectroscopy of Sub-picosecond Laser-Produced Plasmas beyond 50 keV*1

Three-energy focusing Laue monochromator for the diamond light source x-ray pair distribution function beamline I15-1

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