2018
DOI: 10.1017/s0007114518002441
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A single dose of beetroot juice improves endothelial function but not tissue oxygenation in pregnant women: a randomised clinical trial

Abstract: Beetroot juice (BJ) consumption has been associated with improved cardiovascular health owing to an increase in NO bioconversion. This study evaluates the effect of BJ consumption on macrovascular endothelial function (flow-mediated dilation (FMD)) and muscle oxygen saturation (StO2) parameters in pregnant women within a randomised, crossover, double-blind design in which twelve pregnant women consumed a single dose (140 ml) of BJ or placebo (PLA). Urinary nitrate was assessed before (T0) and 150 min after BJ/… Show more

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Cited by 29 publications
(21 citation statements)
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“…After a 20‐min recovery period from the FMD measurement, microvascular function was assessed as previously described . In brief, the NIRS device (PortaMon, Artinis, Medical Systems) was placed on the skin, over the dominant forearm (flexor carpi radialis) muscle, exactly at 5 cm distal of the medial epicondyle of the humerous and a pneumatic cuff was wrapped around the antecubital fossa (2 cm above the medial epicondyle of the humerous).…”
Section: Methodsmentioning
confidence: 99%
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“…After a 20‐min recovery period from the FMD measurement, microvascular function was assessed as previously described . In brief, the NIRS device (PortaMon, Artinis, Medical Systems) was placed on the skin, over the dominant forearm (flexor carpi radialis) muscle, exactly at 5 cm distal of the medial epicondyle of the humerous and a pneumatic cuff was wrapped around the antecubital fossa (2 cm above the medial epicondyle of the humerous).…”
Section: Methodsmentioning
confidence: 99%
“…After a 20-min recovery period from the FMD measurement, microvascular function was assessed as previously described. 17,24,25 In Figure 1A.…”
Section: Microvascular Functionmentioning
confidence: 99%
“…In terms of translation to pregnant women, two recent trials (Ormesher et al 2018;Volino-Souza et al 2018), including one by our own group (Ormesher et al 2018), have investigated whether maternal BRJ supplementation could be beneficial in pregnant women. Notably, in both of these studies, a double-blind placebo-controlled design was used, and hence only BRJ+ and BRJ− arms were included.…”
Section: Reduced Utero-placental Blood Flow and Elevated Vascular Resmentioning
confidence: 99%
“…This effect is mediated by a modulation of endothelial function [63]. In randomized, crossover, double-blind study has been shown that the consumption of the single dose (140 ml) of red beetroot juice improved macrovascular endothelial function, but not muscle oxygen saturation parameters in pregnant women [64].…”
Section: Effect On the Cardiovascular System And Endurance Exercise Pmentioning
confidence: 99%