A Six Sigma DMAIC methodology as a support tool for Health Technology Assessment of two antibiotics

Ponsiglione, Alfonso Maria; Ricciardi, Carlo; Improta, Giovanni; Orabona, Giovanni Dell’Aversana; Sorrentino, Alfonso; Amato, Francesco; Romano, Maria

doi:10.3934/mbe.2021174

Cited by 28 publications

(14 citation statements)

References 40 publications

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“…Additionally, this study includes a methodology component called economic and productivity evaluation to assess the potential impacts generated by the proposed improvements for the secondary distribution system in the company. DMAIC methodology represents a systematic analytic procedure that could be generalized to a wide range of applications [64]; therefore, the methodological approach based on the DMAIC is appropriate since it allows for developing improvement proposals based on the data analysis from the secondary distribution network using statistical techniques and process management. Figure 1 shows the stages of the methodological framework to achieve the objective of this study.…”

Section: Methodsmentioning

confidence: 99%

ICT Validation in Logistics Processes: Improvement of Distribution Processes in a Goods Sector Company

2021

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This article aims to improve the secondary distribution process in a mass consumer company implementing technologies, such as transport management system (TMS) to achieve the objectives set by the company. A DMAIC based methodology is proposed to define and solve structured problems related to secondary distribution, following the performance of the process based on critical to logistics (CTL) factors. The methodology prioritized the design of a master plan for the secondary distribution and the characterization of the secondary distribution process, defining the principal technologies that should compose the business architecture of the secondary distribution, with emphasis on the TMS due to its significant impact and relevance for planning, execution, and control of the distribution process. This study replaces the control component of the DMAIC with the assess component to perform the economic and productivity evaluation of the implementation of a TMS since the improvement proposals were formulated and evaluated. The results show that TMS allows the reduction of delivery time variability, order processing time, voided invoices, distribution costs, the increase in customer service and efficiency in the distribution operation and generates profitability for the medium and long term.

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Section: Methodsmentioning

confidence: 99%

ICT Validation in Logistics Processes: Improvement of Distribution Processes in a Goods Sector Company

2021

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“…The aim of this work is to carry out an HTA procedure to compare two different surgical procedures using an adapted DMAIC cycle of SS, as recently performed in literature [ 38 , 39 ]. The rationale is to produce helpful data for the evaluation of the best surgical technique, and therefore, more generally, for the decision-making and management processes of health governance.…”

Section: Introductionmentioning

confidence: 99%

Comparing Two Approaches for Thyroidectomy: A Health Technology Assessment through DMAIC Cycle

Ricciardi

Gubitosi

Vecchione³

et al. 2022

Healthcare

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Total thyroidectomy is very common in endocrine surgery and the haemostasis can be obtained in different ways across surgery; recently, some devices have been developed to support this surgical phase. In this paper, a health technology assessment is conducted through the define, measure, analyse, improve, and control cycle of the Six Sigma methodology to compare traditional total thyroidectomy with the surgical operation performed through a new device in an overall population of 104 patients. Length of hospital stay, drain output, and time for surgery were considered the critical to qualities in order to compare the surgical approaches which can be considered equal regarding the organizational, ethical, and security impact. Statistical tests (Kolmogorov–Smirnov, t test, ANOVA, Mann–Whitney, and Kruskal–Wallis tests) and visual management diagrams were employed to compare the approaches, but no statistically significant difference was found between them. Considering these results, this study shows that the introduction of the device to perform total thyroidectomy does not guarantee appreciable clinical advantages. A cost analysis to quantify the economic impact of the device into the practice could be a future development. Healthy policy leaders and clinicians who are requested to make decisions regarding the supply of biomedical technologies could benefit from this research.

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“…The most important challenge for healthcare systems is to provide assistance, improving efficiency, productivity, and the appropriateness and quality of care and its departments and for this aim, various tools and approaches have been proposed in the literature so far in different healthcare settings and for different objectives aimed at improving the quality of the provided services. [4][5][6][7][8][9] However, no objective and officially parameters that can assess the true efficiency and quality of these EDs Open access were recognised. This study aims to review the literature on the issues encountered in the efficiency of EDs worldwide.…”

Section: Introductionmentioning

confidence: 99%

Efficiency measures of emergency departments: an Italian systematic literature review

et al. 2021

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Life expectancy globally increased in the last decades: the number of people aged 65 or older is consequently projected to grow, and healthcare demand will increase as well. In the recent years, the number of patients visiting the hospital emergency departments (EDs) rocked in almost all countries of the world. These departments are crucial in all healthcare systems and play a critical role in providing an efficient assistance to all patients. A systematic literature review covering PubMed, Scopus and the Cochrane Library was performed from 2009 to 2019. Of the 718 references found in the literature research, more than 25 studies were included in the current review. Different predictors were associated with the quality of EDs care, which may help to define and implement preventive strategies in the near future. There is no harmonisation in efficiency measurements reflecting the performance in the ED setting. The identification of consistent measures of efficiency is crucial to build an evidence base for future initiatives. The aim of this study is to review the literature on the problems encountered in the efficiency of EDs around the world in order to identify an organisational model or guidelines that can be implemented in EDs to fill inefficiencies and ensure access optimal treatment both in terms of resources and timing. This review will support policy makers to improve the quality of health facilities, and, consequently of the entire healthcare systems.

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A Six Sigma DMAIC methodology as a support tool for Health Technology Assessment of two antibiotics

Cited by 28 publications

References 40 publications

ICT Validation in Logistics Processes: Improvement of Distribution Processes in a Goods Sector Company

ICT Validation in Logistics Processes: Improvement of Distribution Processes in a Goods Sector Company

Comparing Two Approaches for Thyroidectomy: A Health Technology Assessment through DMAIC Cycle

Efficiency measures of emergency departments: an Italian systematic literature review

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