A specific antioxidant peptide: Its properties in controlling oxidation and possible action mechanism

Yang, Qian; Cai, Xiaoyan; Ana, Yan; Tian, Yongtao; Du, Ming; Wang, Shaoyun

doi:10.1016/j.foodchem.2020.126984

Cited by 60 publications

(39 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, with longer lifetimes than peroxy-radicals, much more stable phenoxy radicals inhibit any reverse reaction or the propagation of the radical-mediated peroxiding chain reaction [ 31 ]. According to the reaction mechanism of ATVY against ABTS• + [ 22 ], peroxy-radicals may be linked to the ortho-position of the phenoxy in Tyr by covalent bonds. The Tyr- residue could also be a hydrogen donor in this system.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Impact of Tetrapeptide-FSEY on Oxidative and Physical Stability of Hazelnut Oil-In-Water Emulsion

Shi

Liu

et al. 2021

Foods

View full text Add to dashboard Cite

This study investigates the antioxidant behaviors of a hazelnut tetrapeptide, FSEY (Phe-Ser-Glu-Tyr), in an oil-in-water emulsion. The emulsion was prepared with stripped hazelnut oil at a ratio of 10%. O/W emulsions, both with and without antioxidants (FSEY and TBHQ), were incubated at 37 °C. The chemical stabilities, including those of free radicals and primary and secondary oxidation productions, along with the physical stabilities, which include particle size, zeta-potential, color, pH, and ΔBS, were analyzed. Consequently, FSEY displayed excellent antioxidant behaviors in the test system by scavenging free lipid radicals. Both primary and secondary oxidation products were significantly lower in the FSEY groups. Furthermore, FSEY assisted in stabilizing the physical structure of the emulsion. This antioxidant could inhibit the increase in particle size, prevent the formation of creaming, and stabilize the original color and pH of the emulsion. Consequently, FSEY may be an effective antioxidant additive to use in emulsion systems.

show abstract

Section: Resultsmentioning

confidence: 99%

“…DPPH radicals and ABTS radicals were used to evaluate the capability of FSEY against other radicals. The radical scavenging activity of the sample was evaluated according to a previous method with some modifications [ 22 ]. Briefly, FSEY–water solutions were mixed with 0.1 mmoL/L DPPH (prepared in ethanol) at a ratio of 1:1 ( v / v ).…”

Section: Methodsmentioning

confidence: 99%

Impact of Tetrapeptide-FSEY on Oxidative and Physical Stability of Hazelnut Oil-In-Water Emulsion

Shi

Liu

et al. 2021

Foods

View full text Add to dashboard Cite

show abstract

“…The ability of PGP and PGPHs to scavenge the DPPH radical was measured using the method of Yang et al [6] with minor modifications. An aliquot of 0.5 mL of PGP and PGPHs (0.5 mg/mL) were mixed with the same volume of DPPH (0.1 mM) in 95% ethanol.…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

“…Compared with natural antioxidants, synthetic antioxidants may have potential risks. Therefore, researchers are working to develop natural antioxidants from food which can be used to prevent oxidation in place of synthetic antioxidant food additives with side effects [6].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Antioxidant Protein Hydrolysates from Pleurotus geesteranus and Their Protective Effects on H2O2 Oxidative Damaged PC12 Cells

Liao

Zhu

et al. 2020

Molecules

View full text Add to dashboard Cite

Pleurotus geesteranus is a promising source of bioactive compounds. However, knowledge of the antioxidant behaviors of P. geesteranus protein hydrolysates (PGPHs) is limited. In this study, PGPHs were prepared with papain, alcalase, flavourzyme, pepsin, and pancreatin, respectively. The antioxidant properties and cytoprotective effects against oxidative stress of PGPHs were investigated using different chemical assays and H2O2 damaged PC12 cells, respectively. The results showed that PGPHs exhibited superior antioxidant activity. Especially, hydrolysate generated by alcalase displayed the strongest 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (91.62%), 2,2-azino-bis (3-ethylbenzothia zoline-6-sulfonic acid) (ABTS) radical scavenging activity (90.53%), ferric reducing antioxidant power, and metal ion-chelating activity (82.16%). Analysis of amino acid composition revealed that this hydrolysate was rich in hydrophobic, negatively charged, and aromatic amino acids, contributing to its superior antioxidant properties. Additionally, alcalase hydrolysate showed cytoprotective effects on H2O2-induced oxidative stress in PC12 cells via diminishing intracellular reactive oxygen species (ROS) accumulation by stimulating antioxidant enzyme activities. Taken together, alcalase hydrolysate of P. geesteranus protein can be used as beneficial ingredients with antioxidant properties and protective effects against ROS-mediated oxidative stress.

show abstract

“…[46] They work together in order to carry out intracellular antioxidants, maintain the balance of oxygen free radicals in the body, protect the cell membrane, and ensure the integrity of cell structure and function . [47,48] The principal sources of free radicals in the body and the damage results and the antioxidant defense mechanism of free radical damage are shown in Figure 1.…”

Section: Antioxidant Sesame Peptidesmentioning

confidence: 99%

Advancement of the preparation methods and biological activity of peptides from sesame oil byproducts: a review

Shao

Zhang

et al. 2020

International Journal of Food Properties

View full text Add to dashboard Cite

A specific antioxidant peptide: Its properties in controlling oxidation and possible action mechanism

Cited by 60 publications

References 34 publications

Impact of Tetrapeptide-FSEY on Oxidative and Physical Stability of Hazelnut Oil-In-Water Emulsion

Impact of Tetrapeptide-FSEY on Oxidative and Physical Stability of Hazelnut Oil-In-Water Emulsion

Preparation of Antioxidant Protein Hydrolysates from Pleurotus geesteranus and Their Protective Effects on H2O2 Oxidative Damaged PC12 Cells

Advancement of the preparation methods and biological activity of peptides from sesame oil byproducts: a review

Contact Info

Product

Resources

About