A Standard Penicillinase Preparation

Abstract

(1) Standardization of penicillinase has been made possible by the method for its assay. (2) A purified, dried and sterile penicillinase has been found to be a penicillin-inactivator superior to Clarase for the penicillin sterility test. (3) Preliminary studies show this penicillinase preparation may be used for inactivating penicillin in exudates of body fluids.

Inactivation of the Germicidal Action of Quaternary Ammonium Compounds*

“…Additional examples of methods that are used for inactivating the antibacterial prop-.erties of various compounds may be found in the following combinations : sodium thiosulfate versus chlorine (3, 4) ; p-aminobenzoic acid versus sulfanilamide (5, 6 ) ; penicillinase versus penicillin (7,8,9); ferric chloride versus phenol (10); and glucose versus streptomycin (11).…”