Results from an experimental profile loss study are presented of an additive manufactured linear turbine cascade placed in the test section of a closed-loop organic vapor wind tunnel. This test facility at Muenster University of Applied Sciences allows the investigation of high subsonic and transonic organic vapor flows under ORC turbine flow conditions at elevated pressure and temperature levels. An airfoil from the open literature was chosen for the cascade, and the organic vapor was Novec 649TM. Pitot probes measured the flow field upstream and downstream of the cascade. The inflow turbulence level was 0.5%. The roughness parameters of the metal-printed blades were determined, and the first set of flow measurements was performed. Then, the blade surfaces were further finished, and the impact of roughness on profile losses was assessed in the second flow measurement set. Although the Reynolds number level was relatively high, further surface treatment reduces the profile loss noticeably in organic vapor flows through the printed cascade.