A Study Comparing Outcomes of Appendectomy between HIV-Infected and HIV-Negative Patients

Sobnach, Sanju; Ede, Chikwendu; Linde, G. Van Der; Klopper, J. F.; Bhyat, Ahmed; Kahn, Delawir

doi:10.21614/chirurgia.114.4.467

Cited by 6 publications

(16 citation statements)

References 26 publications

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“…Blumberg's sign was present in 90% of cases in our study the defense of the right iliac fossa was present in 96.7%. This defense of the right iliac fossa has been found in all series [11] [16].…”

Section: Physical Signsmentioning

confidence: 64%

Epidemiological-Clinical and Therapeutic Aspects of Acute Appendicitis at the Reference Health Center of Commune III (C.S.Ref CIII) of the District of Bamako

Boubacar¹,

Idrissa²,

Dianguina³

et al. 2023

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Objectives: It was to determine the epidemiological-clinical and therapeutic aspects of acute appendicitis at the Reference Health Center of Commune III of the district of Bamako. Methodology: This was a prospective study from January 1 to December 31, 2020 including patients operated for acute appendicitis and confirmed at histology and cases of abscess and appendicular plastron. Results: We collected 60 cases of acute appendicitis. They accounted for 17.29% of surgical indications. The average age of our patients was 25.5 years. The male sex was the most represented at 63% with a sex ratio of 1.72. The Pain in the right iliac fossa was the most represented reason for consultation with 76.7%. It was at the type of bite 70% of the cases. On physical examination the defense of the right iliac fossa was present in 96.7%. Digestive signs were marked by nausea 28.4% (17 patients) and vomiting 25% (15 patients). The digital rectal exam was painful to the right of the Douglas fir in 76.7% of our patients. In biology a complete blood count (CBC) performed in all our patients has objectified hyper leukocytosis in 80% of cases. The reactive protein (CRP) performed in 36 patients was elevated with values between 18 and 46 mg/ml. The imaging performed was an abdominal ultrasound that found a roundel image of the appendix with increased size in 65%. Surgical treatment consisted of classical Mac Burney appendectomy in 54 patients (90%). The gesture performed was an appendectomy in all our patients. All our appendectomy parts were sent for pathological examination.

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Section: Physical Signsmentioning

confidence: 64%

Epidemiological-Clinical and Therapeutic Aspects of Acute Appendicitis at the Reference Health Center of Commune III (C.S.Ref CIII) of the District of Bamako

Boubacar¹,

Idrissa²,

Dianguina³

et al. 2023

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“…The causative agents including mycobacterium, cytomegalovirus, cryptosporidium, pneumococcus, Amoebic appendicitis, Pill Impaction and IRIS have been reported as AA in HIV patients. 6,[13][14][15] There are different conditions in HIV patients which can present as abdominal pain or right iliac fossa pain. For instance, disseminated histoplasmosis and Kaposi's Sarcoma can present as AA.…”

Section: Hiv and Appendicitismentioning

confidence: 99%

“…10 In other studies, no difference was seen in the complication rate, length of hospital stays, and mortality between HIV-positive and HIV-negative patients. 11,13 In one case study, pill impaction was found in appendiceal orifice with HIV patient. 14 In summary, it is possible that HIV can influence the appendix in different ways: (1) HIV virus directly affects the appendix, (2) opportunistic infections, (3) IRIS and (4) high levels of perioperative complications.…”

Section: Epidemiologymentioning

confidence: 99%

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Acute appendicitis in people living with HIV: What does the emergency surgeon needs to know?

et al. 2021

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Acute appendicitis is among the commonest surgical emergencies seen in an acute setting. Individuals living with the Human Immunodeficiency Virus (HIV) and/or the Acquired Immunodeficiency Syndrome (AIDS) have an increased risk of encountering complications with acute appendicitis. We conducted a literature search using the words appendicitis and HIV in google scholar, Medline, Scopus and PubMed. The search also extended to cover HIV presented with acute appendicitis, their outcome during and following the management of acute appendicitis. Several studies showed that HIV is associated with a higher rate of acute appendicitis than the general population. HIV can directly affect the appendix, through opportunistic infections, immune reconstitution inflammatory syndrome associated with start of antiretroviral medication. High index of suspicion is needed to exclude conditions that mimic acute appendicitis (abdominal tuberculosis, pyelonephritis, cytomegalovirus, cryptosporidium, pneumococcus, Amoebic appendicitis and pill impaction). The clinical presentation may not be typical of acute appendicitis and can be associated with low white cell count and variable fever. The Alvarado score for predicting acute appendicitis can be used and more research is needed to establish cut-off point value. Computed tomography scan and ultrasound are widely used in clinical diagnosis. Importantly, acute appendicitis with HIV/AIDS can be associated with high rate of post-surgical complications like infections, delay of healing, perforation, peritonitis, intra-abdominal abscess and longer hospital stay. HIV/AIDS with acute appendicitis is complex condition. Therefore, we conclude that patients with known HIV and acute appendicitis should also be managed in close liaison with HIV physicians during, before and after surgical treatment.

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“…As this patient population grows, more such patients will undergo surgery. Patients with HIV are generally immunocompromised, and HIV infection is regarded as a perioperative risk associated with higher morbidity, more severe postoperative complications, and longer hospital stays [ 2 – 5 ]. Thus, surgeons must assess HIV-positive [HIV (+)] patients carefully to predict their postoperative risk and evaluate the benefit–risk balance of surgery.…”

Section: Introductionmentioning

confidence: 99%

Surgical management of appendicitis in patients with human immunodeficiency virus (HIV) positivity: a propensity score-matched analysis in a base hospital for HIV treatment in Japan

et al. 2023

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A Study Comparing Outcomes of Appendectomy between HIV-Infected and HIV-Negative Patients

Cited by 6 publications

References 26 publications

Epidemiological-Clinical and Therapeutic Aspects of Acute Appendicitis at the Reference Health Center of Commune III (C.S.Ref CIII) of the District of Bamako

Epidemiological-Clinical and Therapeutic Aspects of Acute Appendicitis at the Reference Health Center of Commune III (C.S.Ref CIII) of the District of Bamako

Acute appendicitis in people living with HIV: What does the emergency surgeon needs to know?

Surgical management of appendicitis in patients with human immunodeficiency virus (HIV) positivity: a propensity score-matched analysis in a base hospital for HIV treatment in Japan

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