A Study of Prescribing Pattern of Non Steroidal Anti Inflammatory Drugs in Orthopedic Out Patient Department at a Tertiary Care Hospital

Abstract

To determine the pattern of NON STEROIDAL ANTI INFLAMMATORY DRUGS prescribing for arthritic and non-arthritic conditions in orthopedic outpatient department. METHODOLOGY: 100 prescription duplicate collected and analyzed prospectively for the pattern of NSAID prescription for arthritic and non-arthritic conditions; the drug formulation, route, frequency, duration of admission and concomitant medications results. NSAID were prescribed for nontraumatic musculo skeletal 35% pain, 25% post traumatic pain, 20% osteoarthritis, 10% postoperative pain, 3% ankylosing spondylitis, 6% degenerative disease of spine, 1% neuralgia. The NSAIDs commonly prescribed were Aceclofenac 45%, Etodolac 20%, Diclofenac 24%, and Ibuprofen 11%. Fixed dose combination of NSAIDs with adjuvante was prescribed in. The adjuvants, included are paracetamol 55.6%, serratopeptidase 32.8%, chlorzoxazone 9.1%, Thiocolchichoside 2.5%. oral formulations of NSAIDs were prescribed in all patients, supplemented by Topical formulations as gel/cream in 15% of subjects. The dosing frequency was BID (65%), OD (25%), TID (2%), SOS (8%). Duration of administration ranged from 5-15 days.other classes of drugs used concomitantly were proton pump inhibitors, calcium supplements, Multivitamins, Anti microbials, Immuno suppressants, and Glucosamine. CONCLUSION: NSAIDs were prescribed empirically for various arthritic and Nonarthritic conditions, frequently as fixed dose combinations [FDC]s with various adjuvants as per the standard guide lines. However patient information was inadequate in most of the prescriptions. Proper patient Assessment deemed necessary for individualizing NSAIDs.