A Study of Relationship Between Serum Esr and CRP in Patients With Ossification of Posterior Longitudinal Ligament

Abstract

Ossification of the posterior longitudinal ligament (OPLL) is seen most commonly in men, in the elderly, and in Asian population [1].The disease usually starts with minimal or no symptoms, but some patients slowly progress to develop symptoms of myelopathy and radiculopathy.The present study aims to find out the relationship between serum CRP and ESR levels in patients with OPLL and its relationship with radiological classification of OPLL. In this cross sectional correlation study we have included all patients fulfilling the inclusion criteria from the year July 2019 to December 2020 in tertiary care hospital.Our study comprising of total 50 patients will show the relationship between OPLL with level of serum CRP and ESR (normal or raised).In our study it was found that majority of the patients were above 50 years of age with male predominance.In the present study it was found that the level of CRP was raised in 83.4% cases of continuous type,100% cases of localised type,69.2% cases of mixed type and 92.8% cases of segmental type.In the present study it was found that the level of ESR was raised in 83.4% cases of continuous type,66.7% cases of localised type,61.5% cases of mixed type and 75.0% cases of segmental type. It is possible that raised serum levels of CRP and ESR may be associated with OPLL and thus inflammation may be the cause of OPLL.