A Study of the effect of Wedelia calendulacea less. On wound healing in rats

Abstract

The effect of an aqueous extract of the leaves of Wedelia calendulacea Less. on wound healing, in open and sutured wound models, was observed and found to be significant.

Ethnopharmacological approaches to wound healing—Exploring medicinal plants of India

“…Aqueous extract Incision and excision Hedge et al (1994) developed countries too, people are seeking alternative to modern therapies of wound healing like antibiotics, corticosteroids, etc. obviously due to its side effects.…”

Testing Wound-healing Activity in T15 Fibroblast Cultures: A Morphometric Analysis

“…In in vivo techniques, the total duration of the experimental procedure usually needs to be more than 10 days in the absence of microbial contamination or inflammation (2,10). Therefore, open-wound techniques are not useful for the pharmacological screening and bioassay-guided fractionation of plant products, although there are a number of reports which have demonstrated woundhealing properties in a variety of plant products (3,4,(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). It is also difficult to test a series of synthetic compounds for woundhealing activity and to construct structureactivity relationships, which are important for the development of new drugs, by using open-wound techniques.…”