A study of the efficacy and safety of transurethral needle ablation (TUNA®) treatment for benign prostatic hyperplasia

Millard, R. J.; Harewood, Laurence; Tamaddon, K.

doi:10.1002/(sici)1520-6777(1996)15:6<619::aid-nau3>3.0.co;2-i

Cited by 21 publications

(21 citation statements)

References 15 publications

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“…Few studies of TUNA have used relief of urodynamically proven obstruction as an end point [8][9][10][11]. The studies that do use that end point show that TUNA is effective in increasing maximum fl ow rate and decreasing detrusor pressure at maximum fl ow rate.…”

Section: Transurethral Needle Ablationmentioning

confidence: 99%

Urodynamics to guide surgical therapy in LUTS/BPH

Brucker¹,

Jaffe

2009

Curr Bladder Dysfunct Rep

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Section: Transurethral Needle Ablationmentioning

confidence: 99%

Urodynamics to guide surgical therapy in LUTS/BPH

Brucker¹,

Jaffe

2009

Curr Bladder Dysfunct Rep

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“…Some studies examined relief of urodynamically proven obstruction as endpoint [13,[19][20][21]. The two largest series indicated that maximum detrusor pressure decreased significantly after TUNA [19,20].…”

Section: Transurethral Needle Ablation Of the Prostatementioning

confidence: 99%

“…The two largest series indicated that maximum detrusor pressure decreased significantly after TUNA [19,20]. The remaining studies [13,21] suggested that obstruction persisted despite the improvement in subjective and in objective parameters.…”

Section: Transurethral Needle Ablation Of the Prostatementioning

confidence: 99%

Is the minimally invasive treatment as good as transurethral resection for benign prostatic hyperplasia?

Zani

Netto

2007

Int Urol Nephrol

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Despite the development of new technologies, transurethral resection of the prostate (TURP) is still considered the gold standard for surgical treatment of the benign prostate hyperplasia (BPH). In general, new minimally invasive treatments have not demonstrated better outcomes than TURP in evidence based medicine trials published to date, and should be reserved for patients who prefer to avoid surgery, who are unsuitable candidates for surgery or who no longer respond favorably to medication. TUMT and TUNA appears to be more effective than medical therapy but less effective than TURP. Both treatments can be given under topical anesthesia or local prostatic or perineal block. Efficacy of transurethral vaporization appears similar to TURP, but the studies are short-term and the glands operated on are relatively small. In patients with small prostates, the transurethral incision of the prostate can also be a good option, associated with less morbidity than TURP. Bipolar resection of the prostate is similar to TURP in effectiveness, but the data are inconclusive regarding blood loss, length of catheterization and hospital stay. Long-term comparative trials are needed to determine if the minimally invasive therapies are superior to standard TURP.

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“…The majority of data derive from 26 noncomparative studies [2][3][4][6][7][8]10,12,14,17,[20][21][22][23][24][25][26][27], the shortest follow-up being 3 months (650 patients) and the longest being 5 years (394 patients). Improvement of LUTS is stable over time with an average of 53% improvement at 3 months, 59% at 1 year and 51% at 5 years [19 ].…”

Section: Clinical Outcomementioning

confidence: 99%

“…Significant subjective improvement was found in early studies: the International Prostate Symptom Score halved after 6 months and flow rate increased by an average of 50%; positive results were then confirmed in other clinical trials [2][3][4][5]. TUNA was also tested in the management of patients with an indwelling catheter for acute or chronic urinary retention with favourable results [6,7]. Urodynamic investigation of TUNA treatment failed to show a clinically relevant improvement of voiding dynamics [8].…”

Section: Introductionmentioning

confidence: 99%