A study of the relationship between ABO blood group and Rh with the amount of IgG antibody titers in recovered corona-inflicted patients

Abstract

Introduction : In pandemic of infectious diseases, antibody evaluation and its effective factors are vital to control public health and eradicate the disease. Evaluation of susceptibility to viral infections among people with different blood groups is considered as an epidemiological indicator. This study aimed to evaluate the level of IgG antibodies for COVID-19 patients in ABO blood groups and Rh. Material and Methods This study was performed on 237 recovered corona-inflicted patients. None of these patients had been vaccinated. The level of SARS-CoV-2-specific IgG antibody titer was measured. Also, association between IgG antibody titer with RH and blood group types was examined. Results This study showed a significant correlation between IgG levels of individuals with their age. Also, IgG antibody titer was higher in men than women. In addition, patients with an age range of 20 to 60 years compared to individuals under 20 years and over 60 years had higher IgG. There was no significant relationship between blood groups and Rh with the amount of IgG antibody titers. Conclusions Our finding give us a valuable insight into the importance of considering SARS-CoV-2-specific IgG antibody titer as an outstanding marker of COVID-19. Although no significant relationship was found between blood type and RH with the IgG antibody titer level of COVID-19 patients. To understand the prevalence of the disease in the community and its epidemiological control, IgG antibody titer test is recommended to determine the serological level of the community.