A Study on Adverse Drug Reactions and Their Risk Factors of Anti- Asthmatic Agents Among Garments Dust-Induced Asthmatic Patients in Manchester of South India

Abstract

Objective: Adverse drug reactions (ADRs) are well known to occur with any class of drugs when used in normal doses for the management of diseases. The main aim of the study was to detect and analyze ADRs in patients with bronchial asthma in a Coimbatore zone.Methods: This was an observational, voluntary reporting study. The study was conducted in and around Coimbatore. Samples are collected in all age groups. We are taken support of “Suspected ADR” reporting form from Indian pharmacopoeia commission to collect samples.Results: A total of 1163 ADRs were reported by patients during the study period with male predominance over female. The average age of the patients in the study was found to be 30–60 years. The majority of ADR occurred in the age group 30–60 years, the average duration of bronchial asthma in this study was found to be 3 years. The most commonly occurred ADRs were beclomethasane-induced seizures, salbutamol-induced tremor, anorexia, and nausea, and nausea, salmeterol-induced tremor, and montelukast-induced angioedema were also common.Conclusion: An ADR due to oral anti-asthmatic is a frequent problem. Few multicenter studies are needed for a strong anti-asthmatic drug ADRs database in India.