A study on carotid artery intima–media thickness and metabolic risk factors in overweight and obese Indian children

Sajja, Vignatha; Dhivyalakshmi, Jeevarathnam; James, Saji; Rathinasamy, Jebaraj

doi:10.1007/s13340-019-00417-6

Cited by 6 publications

(8 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the Sajja study, age and gender had no effect on the mean intimal medial thickness. 26 In contrast, the current study showed a significant correlation between age and CCA-IMT ( P = .000).…”

Section: Discussioncontrasting

confidence: 92%

“…Sajja et al 26 found that children who were overweight or obese had a greater mean CCA-IMT than the children with normal BMI (0.5 ± 0.1 mm vs. 0.34 ± 0.05 mm). In the current study, a significant correlation was observed between BMI and the right CCA-IMT ( P = .000) and between BMI and the left CCA-IMT ( P = .001).…”

Section: Discussionmentioning

confidence: 99%

“…24 According to the study results provided by Luo, among patients between the ages of 35 and 65 years, the left CCA-IMT exhibited a significant increase in thickness compared to the right (P = .01-.05), and the difference was significant (P = .001) as both CIMTs increased in size with age. 25 Sajja et al 26 found that children who were overweight or obese had a greater mean CCA-IMT than the children with normal BMI (0.5 ± 0.1 mm vs. 0.34 ± 0.05 mm). In the current study, a significant correlation was observed between BMI and the right CCA-IMT (P = .000) and between BMI and the left CCA-IMT (P = .001).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Sonographic Association of Common Carotid Artery Intima-Media Thickness With Age, Obesity, and Hypertension

Ateeq,

Farooq,

Fatima

et al. 2023

Journal of Diagnostic Medical Sonography

View full text Add to dashboard Cite

Objective: The intima-media thickness (IMT) of the common carotid artery (CCA) can indicate cardiovascular and cerebrovascular disease risk, which could aid in early disease identification and prevention. This study was designed to correlate carotid artery IMT with age, obesity, diabetes, and hypertension using sonography. Materials and Methods: This cross-sectional cohort study included 300 individuals of all ages selected through convenient sampling at a university clinic in Lahore from November 2022 to February 2023. An Xario XG ultrasound equipment system (Toshiba, Tokyo, Japan) and a 7.5- to 10-MHz linear transducer was used to examine the patients. Results: The CCA-IMT was evaluated in 300 individuals (mean age 36.83 years). Significant statistical differences were observed between hypertensive/non-hypertensive and diabetic/non-diabetic individuals ( P < .05). CCA-IMT was positively correlated with age and higher in obese/overweight individuals. Conclusion: This large cohort study found a significant difference in CCA-IMT between hypertensive/diabetic and normal individuals. CCA-IMT was positively correlated with age and body mass index.

show abstract

Section: Discussioncontrasting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Sonographic Association of Common Carotid Artery Intima-Media Thickness With Age, Obesity, and Hypertension

Ateeq,

Farooq,

Fatima

et al. 2023

Journal of Diagnostic Medical Sonography

View full text Add to dashboard Cite

show abstract

“…IMT has been suggested as a screening tool for both children and adults who are overweight/obese. [34][35][36] When combined with preterm birth, one would expect a correlation between risk factors and increased IMT in our study population.…”

Section: Discussionmentioning

confidence: 81%

Measuring Carotid Intima-Media Thickness in Young Adults Born Preterm: Comparison of Manual Versus Semi-automated B-Mode Ultrasound

Jalbout

Flahault

Shahi

et al. 2023

Journal for Vascular Ultrasound

View full text Add to dashboard Cite

Introduction: Young adults born very preterm have increased cardiovascular risks. While intima-media thickness of the common carotid artery is an early marker of atherosclerosis in adults, the most reliable method of its measurement is not established in this population. The purpose of this study is to compare manual and semi-automated B-mode ultrasound intima-media thickness measurement techniques in adults born very preterm and full-term. Methods: Intima-media thickness was measured in adults 18 to 29 years born very preterm (<30 weeks’ gestation) or full-term (≥37 weeks’ gestation) using B-mode ultrasound. Analyses included intraclass correlation coefficient (ICC) and relationships with prematurity status, age, body mass index, and metabolic and respiratory comorbidities. Results: There were 86 preterm-born participants (58% women) and 85 full-term (56% women), mean age 23 ± 2 years. Intra-observer agreement was better using semi-automated (ICC = 0.89; 95% confidence interval (CI) = [0.86-0.91]) than manual measurement (ICC = 0.73; 95% CI = [0.65-0.79]). Measures obtained using both techniques did not detect any differences according to prematurity status, did not correlate with age, and moderately correlated with body mass index. The semi-automated technique showed higher intima-media thickness values in men vs women and overall gave higher values. Results obtained through both techniques moderately correlated with each other when looking at subgroups: preterm group ICC of 0.53, full-term group ICC of 0.62. Conclusion: Manual and semi-automated intima-media thickness measurements moderately correlate in young adults. The semi-automated technique is more reproducible. Both techniques are useful in discriminating intima-media thickness according to weight. This study identifies variance of results according to different techniques of measurements. Adherence to a single technique is recommended in young adults born prematurely. Clinical implication includes adherence to the same technique for risk stratification and for follow-up of these patients.

show abstract

“…CIMT was measured as 0.46 mm in obese children. However, in the study by Vignatha Sajja et al, 40 the CIMT value of obese patients was found to be 0.50 mm, and the high CIMT value was evaluated as 0.45 mm. Since the CIMT of obese patients in our study was not very high, a positive correlation with fibrin monomers may not be found.…”

Section: Discussionmentioning

confidence: 91%

The relation between increased carotid intima‐media thickness with fibrin monomers in obese children

et al. 2021

View full text Add to dashboard Cite

Aim: This study aimed to investigate the association between carotid intima-media changes that play a part in the atherosclerotic process in childhood obesity and fibrin monomers as an important indicator of fibrin plaque.Methods: This is a cross-sectional study of obese children and non-obese healthy control subjects. Height, weight, body mass index, waist/hip ratio, systolic/diastolic blood pressures were recorded, in addition, biochemistry, haemogram, fibrin monomers and d-dimer were measured in both groups. Right and left common carotid intima-media thicknesses were measured by ultrasonography and mean carotid intima-media thickness was calculated.Results: Obese children (n = 89, 46.1% girls, median age: 12.6 ± 2.3 years) and healthy control group (n = 40, 52.5% girls, median age: 13.2 ± 2.2 years) were comparable in terms of gender, age and puberty stage. Mean carotid intima-media thickness was higher in obese children than the healthy control group (P = .002). There was no difference between the two groups in terms of fibrin monomers and d-dimer levels. In obese children, there was a weak negative correlation between mean carotid intimamedia thickness and fibrin monomers (P = .030, r = −0.233). Conclusion:In obese children, mean carotid intima-media thickness was determined higher, as an early indicator of atherosclerosis. We want to emphasise that obese children are at risk for cardiovascular disease and should be evaluated in terms of atherosclerosis. This study investigates the relation between increased carotid intimamedia thickness and fibrin monomers, in children, the first time in Literature. What's knownIt is possible to reveal the early period of the atherosclerosis process by showing carotid intimamedial thickness. Fibrin is a major component of many atherosclerotic plaques. What's newOur study investigated the relationship between mean carotid intima-media thickness in childhood obesity and fibrin monomers. But no positive correlation was found between fibrin monomers and the carotid intima-media thickness.

show abstract

A study on carotid artery intima–media thickness and metabolic risk factors in overweight and obese Indian children

Cited by 6 publications

References 21 publications

Sonographic Association of Common Carotid Artery Intima-Media Thickness With Age, Obesity, and Hypertension

Sonographic Association of Common Carotid Artery Intima-Media Thickness With Age, Obesity, and Hypertension

Measuring Carotid Intima-Media Thickness in Young Adults Born Preterm: Comparison of Manual Versus Semi-automated B-Mode Ultrasound

The relation between increased carotid intima‐media thickness with fibrin monomers in obese children

Contact Info

Product

Resources

About