A Study on Patients With Peptic Ulcer Perforation With Respect to Aetiology and Factors Affecting Outcome of Management

Rajappan, Yeganathan; Veerasamy, Nagarajan; Ashokkumar, Mahalakshmi; Thangavelu, Manimaran; Kanthan, Anandan

doi:10.14260/jemds/2016/883

Cited by 2 publications

(1 citation statement)

References 18 publications

(14 reference statements)

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“…In our study, the majority of study participants reported history of alcohol consumption (54.3%) and previous NSAID use (71.6%) but only 32.1% smoked cigarette. These factors have been associated with peptic ulcer perforation in previous studies [ 18 ].…”

Section: Discussionmentioning

confidence: 97%

Factors associated with peptic ulcer perforations in Uganda: a multi-hospital cross-sectional study

Edyedu,

Okedi,

Muhumuza

et al. 2024

BMC Gastroenterol

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Introduction Perforated peptic ulcer is the worst complication of peptic ulcer disease whose burden is disproportionately higher in low-income settings. However, there is paucity of published data on the patterns of perforated peptic ulcer in the region. The aim of this study was to determine the factors associated with anatomical patterns of peptic ulcer perforation, as well as the clinical, socio-demographic, and anatomical patterns among patients in Uganda. Methods This was a cross sectional study that enrolled 81 consecutive patients with perforated peptic ulcers. Using a structured pretested questionnaire the social demographic and clinical characteristics were obtained. At surgery, the patterns of the perforations were determined. Logistic regression was done in SPSS version 22 to determine the factors associated with the anatomical patterns. Results Perforated peptic ulcer disease was more prevalent among males (79.5%), peasants (56.8%) and those from rural areas (65.4%). Majority of study participants were of blood group O (43.2%). Gastric perforations were more common (74.1%). Majority of the perforations were found anteriorly (81.5%). Being a casual laborer was independently associated with lower odds of having a gastric perforation compared to being a peasant farmer (P < 0.05). Conclusion Public health campaigns aimed at prevention of peptic ulcer perforations should prioritize the males, peasants and those living in rural areas. When a patient in our setting is suspected to have a peptic ulcer perforation, the anterior part of the stomach should be considered as the most likely site involved more so in peasant farmers.

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Section: Discussionmentioning

confidence: 97%

Factors associated with peptic ulcer perforations in Uganda: a multi-hospital cross-sectional study

Edyedu,

Okedi,

Muhumuza

et al. 2024

BMC Gastroenterol

View full text Add to dashboard Cite

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Factors associated with anatomical patterns of peptic ulcer perforations in a low income country: a multicenter cross sectional study

Edyedu,

Okedi,

Muhumuza

et al. 2023

Preprint

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Introduction: Perforated peptic ulcer is the worst complication of peptic ulcer disease whose burden is disproportionately higher in low-income settings. However, there is paucity of published data on the patterns of perforated peptic ulcer in the region. The aim of this study was to determine the factors associated with anatomical patterns of peptic ulcer perforation, as well as the clinical, socio-demographic, and anatomical patterns among patients in Uganda. Methods: This was a cross sectional study that enrolled 83 consecutive patients with perforated peptic ulcers. At surgery the patterns of the perforations were determined and using a structured pretested questionnaire the social demographic and clinical characteristics were obtained. Logistic regression was done in SPSS version 22 to determine the factors associated with the anatomical patterns. Results: Perforated peptic ulcer disease was more prevalent amongst male (79.5%) peasants (56.8%) of rural residence (65.4%). Majority of study participants were of blood group O (43.2%). The gastric perforations were more common (74.1%) than duodenal, found anteriorly (81.5%) in most of the cases. Being a casual laborer was independently associated with lower odds of having a gastric perforation compared to being a peasant farmer (P < 0.05). Conclusion Public health campaigns aimed at prevention of peptic ulcer perforations should prioritize the males, peasants and those living in rural areas. When a patient in our setting is suspected to have a peptic ulcer perforation, the anterior part of the stomach should be considered as the most likely site involved more so in peasant farmers.

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A Study on Patients With Peptic Ulcer Perforation With Respect to Aetiology and Factors Affecting Outcome of Management

Abstract: BACKGROUNDPerforation peritonitis is one of the commonest surgical emergency encountered by surgeons. The aim of the study is to provide an overview of aetiological factors causing peptic ulcer perforation and the factors affecting the outcome of management.

Cited by 2 publications

References 18 publications

Factors associated with peptic ulcer perforations in Uganda: a multi-hospital cross-sectional study

Factors associated with peptic ulcer perforations in Uganda: a multi-hospital cross-sectional study

Factors associated with anatomical patterns of peptic ulcer perforations in a low income country: a multicenter cross sectional study

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