A study to assess and increase awareness regarding fixed dose combinations among medical undergraduates at Indore and Sagar, Madhya Pradesh, India

Atal, Shubham; Phadnis, Pradeep; Gudsurkar, Gopal

doi:10.18203/2319-2003.ijbcp20160727

Cited by 3 publications

(4 citation statements)

References 3 publications

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“…12 Necessary sensitization and training could reduce the prescription of irrational FDCs, since the implementation of a drug in the treatment lies in the hands of a doctor. 18 "Commercial attitude of industry, irrational prescriptions due to lack of training among physicians are the major causes for the misuse of Fixed dose combination. 19 By all these discussion, it cannot be regarded that Fixed dose combination is not useful.…”

Section: Series1mentioning

confidence: 99%

Knowledge, attitude and prescriptional practice about fixed dose combinations among medical practitioners in tertiary care hospital

Ravichandran¹,

Balamurugan

Shankareshwari³

et al. 2017

Int J Basic Clin Pharmacol

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Background: Fixed dose combination (FDC) are currently most prescribed and misused drug forms. Although fixed dose combinations are clinically better than single dosage forms, improper prescription and large amounts of irrational FDC flooding leads to unwanted financial burden and increased resistance. Therefore a study was carried out to know about the existing scenario about Knowledge Attitude and Practice of Fixed dose combinations among the resident doctors and devise some suggestions for improving the rationality. The objective of the study was to evaluate the knowledge, attitude and prescriptional practice regarding fixed dose combinations among resident doctors working in a Government Theni medical college, Theni.Methods: A cross-sectional descriptive study involving 100 resident doctors was conducted using a pre validated questionnaire containing 21 questions to evaluate the knowledge and prescriptional practice of Fixed Dose Combination among the study participants.Results: Ninety-five percent of the study participants were aware of the Fixed dose combination. Increased compliance and synergistic drug effect are the commonly cited advantages, whereas difficulty in dose adjustment and increased side effects were the commonly told disadvantages. Only 13% of the participants could name a single banned drug. Antibiotics (63%), NSAIDS (18%) were the commonly prescribed FDCs among study participants. Internet (58%), followed by textbook (42%) and colleagues (37%) were the common sources of knowledge about FDCs. Increasing awareness about Essential Medicines List (63%), regular CME (55%) and prior notification (50%) are some of the measures recommended by study participants to improve the awareness.Conclusions: Although the participants are aware of basic knowledge of fixed dose combinations are acceptable, prescribing FDC them often, many of the study participants lack knowledge about the rationality of these drugs. From our study, conducting regular CME’s about new Fixed dose combinations in the medical colleges and periodic notification of FDC’s are some of the suggested approaches to improve the rationality of prescription. Since Internet is listed as the most common source of knowledge about FDC, information about FDC can be sent through mails, text messages, which will play a part in improving the rationality of FDC.

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Section: Series1mentioning

confidence: 99%

Knowledge, attitude and prescriptional practice about fixed dose combinations among medical practitioners in tertiary care hospital

Ravichandran¹,

Balamurugan

Shankareshwari³

et al. 2017

Int J Basic Clin Pharmacol

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“…The analysis of responses for assessing the awareness of students (Table-1)about FDCs, showed that students had a high level of awareness (>80%) regarding some of basic aspects related to FDCs like knowing the term (66.41%), their common use in prescription (67.91%), constitution of FDC (50%), providing benefits to patients by improving compliance (54.47%) and increasing therapeutic response (64.17%). Atal S et al; [8] study among medical undergraduate"s shows similar results.…”

Section: Discussionmentioning

confidence: 55%

A survey to evaluate the awareness of Fixed Dose Combinations (FDCs) among 2nd year medical undergraduates at a rural tertiary care centre, B G Nagara

Manu¹,

Ts²,

M³

et al. 2016

SJAMS

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Combination of two or more active ingredients in a fixed dose ratio is termed as fixed dose combination (FDC). Presently, there is lot of debate over rationality and irrationality of FDCs. This study was focused on medical undergraduates to evaluate the awareness about FDCs as these students are the future practitioners. Like two sides of each coin FDCs do have advantages & disadvantages and it"s up to the physician to misuse it or use it judiciously by maintaining the balance. The objective is to evaluate the awareness of Fixed dose combinations (FDCs) among 2 nd year medical students. A cross-sectional questionnaire-based study was conducted among 2 nd year medical students of AIMS, B G Nagar. Total respondents were 134. Among them 57 participants (42.53%) are male and 77 participants (57.46%) are females. All the participants were within the age group of 19 to 21 years. The analysis of responses for assessing the awareness of students about FDCs, showed that students had a high level of awareness (>80%) regarding some of basic aspects related to FDCs like knowing the term (66.41%), their common use in prescription (67.91%), constitution of FDC (50%), providing benefits to patients by improving compliance (54.47%) and increasing therapeutic response (64.17%). However, students weren"t aware regarding the deeper scientific aspects of FDCs like need for similarity in pharmacokinetics of ingredient drugs (21.64%), rationality & approval status of FDCs available in market. Majority of the students are well aware about the basic concepts of FDCs and their usage; however they are lacking in deeper scientific concepts. It is imperative that the concept of FDCs should be emphasized in sufficient detail to these budding doctors by giving an educational intervention through an interactive lecture presentation; so that the awareness of the students can be increased substantially.

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“…10 The questionnaire was pretested for the content and design on ten pharmacists to clarify any ambiguities and suitable modifications were done. The final version of the questionnaire was used in this study.…”

Section: Questionnairementioning

confidence: 99%

“…9 There is a lack of awareness among patient, pharmacist and physician about FDCs. 10 The present study was undertaken keeping in view the increasing tendency to prescribe FDCs and vital role of pharmacists to ensure their rational use.…”

Section: Introductionmentioning

confidence: 99%

A survey to assess awareness about fixed dose combinations (FDCs) among pharmacists in two Central Kashmir Districts, Srinagar and Budgam, Kashmir, India

Mir

2017

Int J Basic Clin Pharmacol

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Background: FDCs are highly popular in Indian pharmaceutical market. The FDCs have both advantages as well as disadvantages. To be advantageous WHO guidelines for the manufacture and use of FDCs must be strictly followed. Irrational use of FDCs is a major public health problem and leads to increased risk of adverse drug events, higher treatment costs and antimicrobial resistance. FDCs as well as other single component drugs cannot be used rationally unless everyone involved directly or indirectly in the health care profession is involved. Pharmacist is a coordinator between different members of healthcare team and the patients. Hence, his role in safe use of medicines is important. The present study was undertaken to assess the knowledge of pharmacists about FDCs. Methods: A descriptive questionnaire survey was conducted in various government and private pharmacies of two Central Kashmir Districts, Srinagar and Budgam, aiming to assess the knowledge of pharmacists about FDCs. The questionnaires were distributed randomly among 79 pharmacists, out of which 60 returned the completed questionnaire. Results: 55.00% of the respondents knew the basic facts about FDCs. 96.66% knew that FDCs reduced the cost of therapy and 93.33% were aware that FDCs improve patient compliance. 60% answered incorrectly when asked about effect of FDCs on cumulative toxicity. Almost equal percentage (63.33%) answered incorrectly when asked about rationality and ADR profile of FDCs. 83.33% knew that it is difficult to know the offending agent in case ADRs occur after FDC use.78.33% respondents thought that all FDCs are approved by drug regulatory authorities. Conclusions: The study showed that pharmacists had not the enough knowledge about FDCs. Pharmacy students in their formative years of learning should be taught to promote rational use of FDCs as they are the future custodians of technical information on the products available on their domestic market.

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A study to assess and increase awareness regarding fixed dose combinations among medical undergraduates at Indore and Sagar, Madhya Pradesh, India

Cited by 3 publications

References 3 publications

Knowledge, attitude and prescriptional practice about fixed dose combinations among medical practitioners in tertiary care hospital

Knowledge, attitude and prescriptional practice about fixed dose combinations among medical practitioners in tertiary care hospital

A survey to evaluate the awareness of Fixed Dose Combinations (FDCs) among 2nd year medical undergraduates at a rural tertiary care centre, B G Nagara

A survey to assess awareness about fixed dose combinations (FDCs) among pharmacists in two Central Kashmir Districts, Srinagar and Budgam, Kashmir, India

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