A study to assess the occurrence of anaemia and beta-thalassemia in the tribal population residing in the Yadadri-Bhuvanagiri district of Telangana state

Abstract

Background: This study aimed to estimate the prevalence of anaemia and haemoglobinopathies, particularly beta-thalassemia in the tribal population of the Yadadri-Bhuvanagiri district of Telangana. Methods: The sample consisted of a tribal population (Banjara) that visited voluntary blood camps set up in tribal settlements, local schools, and the Gram-panchayat office, in collaboration with local healthcare workers. Haemoglobin measurements (Anaemia) and Mentzer index of whole blood (EDTA) samples were used as diagnostic screening tools for categorising the population at risk of beta-thalassemia. HPLC was used as a confirmatory test. Results: The study included a total of n = 479 (68% females and 32% males) voluntary adult participants of Banjara. Based on the haemoglobin levels, 105 females (32%) were found to be anaemic as compared to 24 males (15.5%). Among the female population, a small percentage of individuals had severe anaemia (1.9%), while most had mild (80%) or moderate anaemia (18%); on the other hand, males primarily had moderate anaemia. Out of the total screened population, 6.7% (5.2% with low Hb levels (anaemic), 3.3% by MI) were found to be thalassemia based on anaemia and Mentzer index as a screening tool. Conclusion: The prevalence of beta-thalassemia was found 6.7% in the Banjara population.