A successful conservative therapy with intraperitoneal OK-432 administration for intractable hepatic lymphorrhea following a radical gastrectomy for gastric cancer. A case report.

Ogasawara, Yuki; Higashi, Kohei; Okano, Kōji

doi:10.3919/jjsa.63.661

Cited by 5 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the intraperitoneal injection of OK-432 is a relatively easy method that can be carried out under local anesthesia, the agent may be diluted in the large space, and there are concerns about potential complications, such as systemic fever, abdominal pain, and adhesive ileus. An average of 3.5 (1–6) injections were required for recovery, with five or more injections needed in about half of all cases [ 4 , 15 , 18 , 22 , 23 , 25 ].…”

Section: Discussionmentioning

confidence: 99%

Successful percutaneous transhepatic lymphangiography and embolization for intractable hepatic lymphorrhea after laparoscopic distal gastrectomy: a case report

et al. 2023

View full text Add to dashboard Cite

Background Hepatic lymphorrhea is a rare and serious complication of surgery for digestive tract cancers and is thought to occur as a result of lymph node dissection of the hepatoduodenal ligament. This complication results in the accumulation of lymphatic fluid, which may in turn lead to nutritional disorders, immune deficiency, and circulation insufficiency. However, there is currently no standard strategy for treating this condition. Case presentation A 49-year-old woman with alcoholic liver damage underwent laparoscopic distal gastrectomy with lymph node dissection for early gastric cancer. Abundant ascites persisted postoperatively, and the fluid was suspected to indicate hepatic lymphorrhea. The patient was re-admitted on postoperative day 26 due to the onset of a brain infarction caused by dehydration. Various conservative treatments for hepatic lymphorrhea were ineffective. She underwent percutaneous transhepatic lymphangiography and embolization on postoperative day 81, with obvious effect. Computed tomography images demonstrated complete disappearance of ascites. Conclusions Postoperative hepatic lymphorrhea is a rare and serious complication of radical surgery for digestive tract cancers. The current case suggests that percutaneous transhepatic lymphangiography and embolization may be a rational treatment option when conservative treatments fail.

show abstract