A Surface Modifier for the Production of Selectively Activated Amino Surface Groups

Abstract

The formation of self-assembled monolayers with the possibility of selective activation is an important goal of surface chemistry. In this work, a new surface modifier which creates amino surfaces based on aminopropylsilatrane (APS) with a protected amino group was obtained. The utilization of protected APS allows producing a self-assembled monolayer (SAM) and obtaining reactive surface amino groups at distinct times. Furthermore, a precise selective deprotection with a further modification of the activated amino groups could be performed without affecting the protected groups. To demonstrate the practical applicability of this modifier, a trinitrotoluene-sensitive sensor based on an ion-sensitive field-effect transistor (ISFET) was obtained.

Compartmentalized Linker Array: A Scalable and Transferrable Microarray Format for Multiplexed Immunoassays

“…They were then stored at 4 and −20 °C for comparison. It has been reported in the literature that APTES can be sensitive to moisture and light; , therefore, we stored the slides in the dark with a desiccant. For the storage in cold conditions, after retrieving the slides from a fridge or a freezer, we waited for approximately 30 min before opening the sealed bags so that the slides were brought to room temperature in a dry environment, avoiding condensation on the slide surface.…”

3-Aminopropylsilatrane and Its Derivatives: A Variety of Applications

“…A new silatrane with a protected amino group was obtained in Ref. [ 92 ]. It was used to design a sensor ( 44 ) ( Figure 12 ) sensitive to trinitrotoluene (electronic nose) for an ion-sensitive field-effect transistor (ISFET).…”