A sustainable strategy for generating highly stable human skin equivalents based on fish collagen

Tan, Shi Hua; Liu, Shaoqiong; Teoh, Swee Hin; Bonnard, Carine; Leavesley, David; Liang, Kun

doi:10.1016/j.bioadv.2024.213780

Cited by 4 publications

(2 citation statements)

References 84 publications

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“…Usually, the amide A band range represents the stretching frequency of N-H, which is between 3400 and 3440 cm À1 , although the number of frequencies can decrease if there is formation of hydrogen bonds, as is the case in this study where the band of amide A are found between 3300 and 3320 cm À1 demonstrating the presence of hydrogen bonds (Valipour et al, 2023), amide I represents the carbonyl group (C O) that presents a stretching vibration between 1600 and 1700 cm À1 , while amide II associated with bending vibrations (N-H) are found between 1550 and 1600 cm À1 and amide III is attributed to the stretching of C N-CH 2 at 1200-1250 cm À1 , similar data were found by different authors (Arumugam et al, 2018;Tan et al, 2024). The results of the thermal analysis by MDSC of the monolayer films are shown in Figure 4 and Table 4.…”

Section: Ftir Of Extracted Collagensupporting

confidence: 83%

“…The collagen obtained presented a fibrous appearance and grayish tones caused by the pigments in the waste; however, after adding saline solution, it turned whitish. The percentage of collagen depending on the residue used usually varies significantly; skin collagen had a yield of 36.5%, values like those reported by Serrano-Gaona (2011) and Tan et al (2024), and in the scales, it was 2.57%, which is lower considering other methods, it is recommended to use the methodology described by Ramos-Collaguazo (2017).…”

Section: Yield Of Extracted Collagenmentioning

confidence: 71%

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Biodegradable monolayer film based on the collagen extracted from Oreochromis sp. processing byproducts blended with chitosan and assembled with PCL and PLA monolayers to form bilayers films

Navarro Arrieta,

Acevedo‐Puello,

Fuentes Ordoñez

et al. 2024

J Food Process Engineering

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The objective of the study is to develop and characterize biodegradable monolayer and bilayer films using collagen extracted from tilapia skin and scales (Oreochromis sp.) with chitosan in combination with biodegradable polyester; polylactic acid (PLA) or polycaprolactone (PCL). Collagen extraction was conducted with acetic acid (0.5 M). Monolayer films based on collagen and chitosan were formed by the casting process with a solution of chitosan (2% w/w) in 1.5% acetic acid, followed by the addition of skin collagen at concentrations of 0.5%, 1%, or 2% w/w, and dried at 45–50°C. The PLA and PCL films were made by compression molding. The films were characterized according to their appearance, structure, morphology, interaction with water, thermal stability, and mechanical and barrier properties. The results indicated that collagen from tilapia skin and scales yielded 36.5% and 2.57%, respectively. The results showed that adding chitosan increased the tensile strength but decreased the elongation of the films. An improvement in thermal stability was observed by increasing the proportion of collagen or chitosan, and it also influenced water solubility and water vapor permeability. Microscopy showed a crack‐free interface between collagen and chitosan. The color of the films varied depending on the composition, highlighting the influence of chitosan in yellow and reddish tones. The bilayers with PLA had lower water vapor permeability and higher gloss compared to those with PCL. Finally, the developed films showed promising properties for their application in food packaging and promote the use of fishery waste.Practical applicationsThe study aims to develop and characterize biodegradable monolayer and bilayer films using collagen extracted from tilapia skin and scales (Oreochromis sp.) combined with chitosan and biodegradable polyester such as polylactic acid or polycaprolactone. The practical applications of this research span a wide range of industrial fields. For instance, monolayer films could be used as sustainable food packaging, offering enhanced barrier properties and biodegradability, thus reducing the environmental impact of conventional packaging. Furthermore, bilayer films could find applications in the healthcare industry, such as controlled‐release drug patches or dressings leveraging the antimicrobial properties of chitosan. This research also provides valuable insights into improving the mechanical, thermal, and barrier properties of biodegradable films, potentially leading to the production of more efficient and versatile materials for a variety of industrial applications.

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Section: Ftir Of Extracted Collagensupporting

confidence: 83%

Section: Yield Of Extracted Collagenmentioning

confidence: 71%

Biodegradable monolayer film based on the collagen extracted from Oreochromis sp. processing byproducts blended with chitosan and assembled with PCL and PLA monolayers to form bilayers films

Navarro Arrieta,

Acevedo‐Puello,

Fuentes Ordoñez

et al. 2024

J Food Process Engineering

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Fish Scales for Wearable Patches: Tailoring Films Assembled From Fish Waste Gelatin, Carbon Dots and Chitin Nanocrystals

Segato,

Calmanti,

Gnoato

et al. 2024

Advanced Sustainable Systems

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The properties of gelatin and collagen extracted from fishery wastes, specifically from mullet (Mugil Cephalus) scales, are modified with the aim to achieve biocompatible films with tunable characteristics to design sustainable UV protection solutions in the healthcare sector. Different additives are used to the scope including plasticizers, cross‐linkers, surfactants and optical modifiers. Carbon dots (CDs) obtained from seabass (Dicentrarchus labrax) scales combined with polysorbate‐20 (PS) as a dispersant agent, enable the fabrication of materials capable of blocking UV radiation almost completely, a crucial feature for dermal contact applications. The addition of hydrophobic surfactants and crosslinkers as citric acid, chitosan and surface deacetylated chitin nanocrystals (CsNCs) allowed to modulate the water adsorption of the films in the range 3–30% and to reach a twofold and 4.5‐fold increase of tensile strength and elastic modulus, respectively, as compared to the neat gelatin film. Moreover, film thickness is shown to be another adjustable parameter to enhance optic, mechanical, and permeation properties: the higher the thickness, the greater the UV‐blocking properties, elongation‐at‐break and water vapor permeability, leading to films with attractive characteristics as wearable patches.

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Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing

Xu,

Fu,

Lun

et al. 2025

Bioactive Materials

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A sustainable strategy for generating highly stable human skin equivalents based on fish collagen

Cited by 4 publications

References 84 publications

Biodegradable monolayer film based on the collagen extracted from Oreochromis sp. processing byproducts blended with chitosan and assembled with PCL and PLA monolayers to form bilayers films

Biodegradable monolayer film based on the collagen extracted from Oreochromis sp. processing byproducts blended with chitosan and assembled with PCL and PLA monolayers to form bilayers films

Fish Scales for Wearable Patches: Tailoring Films Assembled From Fish Waste Gelatin, Carbon Dots and Chitin Nanocrystals

Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing

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