A synbiotic containing Lactobacillus acidophilus CHO-220 and inulin improves irregularity of red blood cells

Ooi, L.-G.; Bhat, Rajeev; Ahmad, Rizwan; Yuen, Kah-Hay; Liong, Min‐Tze

doi:10.3168/jds.2010-3330

Cited by 22 publications

(6 citation statements)

References 42 publications

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“…However, these mechanisms have been proved via in vitro studies and have not been well established in in vitro studies. In the existing literature, the hypocholesterolemic and hypolipidemic effects of prebiotics and probiotics have been reported in various studies ( Liong et al., 2007 , Ooi et al, 2010 ). The cardio-protective indices like CRR, AC, and AIP observed in the present study may also be attributed to the enhanced absorption of micro and macronutrients, including antioxidants, which reduce postprandial lipids associated with oxidative damage and various cardiovascular pathologies ( Martarelli et al., 2011 , Mikelsaar and Zilmer, 2009 ).…”

Section: Discussionmentioning

confidence: 99%

Dietary synbiotic supplementation improves the growth performance, body antioxidant pool, serum biochemistry, meat quality, and lipid oxidative stability in broiler chickens

et al. 2020

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The present study investigated the effects of Lactobacillus acidophilus (LBA) and mannan-oligosaccharides (MOS) supplementation on the production performance, serum biochemistry, antioxidant profile, health indices, meat quality, and lipid oxidative stability of broiler chicken. A total of 252 commercial broiler chickens at 1 d old of uniform body weight were randomly allocated to 6 maize-soybean-based dietary treatments: T 1 (control diet), T 2 ( antibiotic bacitracin methylene di-salicylate [BMD] at 20 mg/kg diet), T 3 (MOS at 0.1% + LBA at 10 6 CFU/g feed), T 4 (MOS at 0.1% + LBA at 10 7 CFU/g feed), T 5 (MOS at 0.2% + LBA at 10 6 CFU/g feed), and T 6 (MOS at 0.2% + LBA at 10 7 CFU/g feed). Each treatment was assigned to 6 replicates of 7 birds. The samples for meat quality and serum biochemistry analysis were taken from 12 birds per treatment (2 birds/replicate). The results revealed better ( P < 0.01) growth performance and production efficiency of birds fed either T 5 or T 6 diet compared to control or BMD supplemented diet and BMD-supplemented birds superseded the control birds. Higher ( P < 0.01) serum and liver antioxidant enzyme activities, meat antioxidant capacity (2, 2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid [ABTS] and 1, 1-diphenyl-2-picrylhydrazyl [DPPH] assays], serum total protein, high-density lipoproteins (HDL) cholesterol ( P < 0.05), and globulin levels ( P < 0.01) were observed in birds fed either T 5 or T 6 diet compared to control or BMD supplemented birds, whereas, lower lipid oxidation ( P < 0.01), cardiac risk ratio, atherogenic coefficient, atherogenic index of plasma, serum glucose, triglyceride, total cholesterol levels ( P < 0.01), and serum albumin-to-globulin ratio ( P < 0.05) were observed in the chickens. The pH of meat from birds fed T 4 , T 5 or T 6 diet was lower ( P < 0.01) compared to control and other treatments. The extract release volume (ERV), water holding capacity (WHC), and protein content of meat were higher ( P < 0.05) in birds fed either T 5 or T 6 diet compared to control or BMD supplemented birds. Thus, it was concluded that the supplementation of 0.2% MOS along with LBA at 10 6 CFU/g is optimum for better growth performance, serum biochemistry, antioxidant profile, health indices, meat quality, and lipid oxidative stability of broiler chickens.

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Section: Discussionmentioning

confidence: 99%

Dietary synbiotic supplementation improves the growth performance, body antioxidant pool, serum biochemistry, meat quality, and lipid oxidative stability in broiler chickens

et al. 2020

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“…While consumption of probiotics is previously known to restore and stabilize the gut microbial population, ongoing researches have suggested that probiotics have potentials in preventing cancer and ageing processes (Xu et al ., 2003), combating hypercholesterolemia (Choi et al ., 2014; Ooi et al ., 2010), and reducing risks and severity of myocardial infarction (Lam et al ., 2012) via various mechanisms of decreased in-vivo toxicity and normalized gut microbiota.…”

Section: Introductionmentioning

confidence: 99%

Application of Probiotics for the Production of Safe and High-quality Poultry Meat

Park¹,

Hamidon²,

Rajangan³

et al. 2016

Korean Journal for Food Science of Animal Resources

104

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Poultry industry has always been a dynamic and integral part of national economies in many countries. Economic losses incur especially in large-scale rearing facilities, often attributed to the deterioration of environmental conditions, poultry exposure to stressors and development of diseases. While antibiotics have been commonly used for prophylactic purposes and as growth stimulants, extensive documentation of antimicrobial resistance among pathogenic bacteria due to indiscriminate utilization of antibiotic in the industry has led to public and governmental outcries. Elimination of antibiotics from poultry production has thus encouraged intensive search for alternatives. In this review, we discuss the immense potential of probiotics to fill the gap as alternative growth promoters and evidences of beneficial effects of probiotic application in poultry production.

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“…A high level of cholesterol in the blood has been associated with increased risk of cardiovascular diseases such as coronary heart disease and stroke. Cardiovascular disease is one of the most common diseases found in developing countries and better management of it is urgently required because of the increased occurrence annually (Ooi et al, 2010). Studies have shown that an increase in cholesterol level of 1 mmol could elevate the risk of coronary heart disease by 35% and the risk of coronary death by 45% (Liong and Shah, 2005).…”

Section: Introductionmentioning

confidence: 99%

Electroporation enhances the ability of lactobacilli to remove cholesterol

Lye

Karim

Rusul

et al. 2011

Journal of Dairy Science

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The objective of the present study was to evaluate the effect of electroporation on the membrane properties of lactobacilli and their ability to remove cholesterol in vitro. The growth of lactobacilli cells treated at 7.5 kV/cm for 4 ms was increased by 0.89 to 1.96 log(10) cfu/mL upon fermentation at 37 °C for 20 h, the increase being attributed to the reversible and transient formation of pores and defragmentation of clumped cells. In addition, an increase of cholesterol assimilation as high as 127.2% was observed for most cells electroporated at a field strength of 7.5 kV/cm for 3.5 ms compared with a lower field strength of 2.5 kV/cm. Electroporation also increased the incorporation of cholesterol into the cellular membrane, as shown by an increased cholesterol:phospholipids ratio (50.0-59.6%) upon treatment at 7.5 kV/cm compared with treatment at 2.5 kV/cm. Saturation of cholesterol was observed in different regions of the membrane bilayer such as upper phospholipids, apolar tail, and polar heads, as indicated by fluorescence anisotropy using 3 fluorescent probes. Electroporation could be a useful technique to increase the ability of lactobacilli to remove cholesterol for possible use as cholesterol-lowering adjuncts in the future.

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A synbiotic containing Lactobacillus acidophilus CHO-220 and inulin improves irregularity of red blood cells

Cited by 22 publications

References 42 publications

Dietary synbiotic supplementation improves the growth performance, body antioxidant pool, serum biochemistry, meat quality, and lipid oxidative stability in broiler chickens

Dietary synbiotic supplementation improves the growth performance, body antioxidant pool, serum biochemistry, meat quality, and lipid oxidative stability in broiler chickens

Application of Probiotics for the Production of Safe and High-quality Poultry Meat

Electroporation enhances the ability of lactobacilli to remove cholesterol

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