A systematic investigation on biological activities of a novel double zwitterionic Schiff base Cu(II) complex

Thalamuthu, S.; Annaraj, B.; Neelakantan, M.A.

doi:10.1016/j.saa.2013.08.065

Cited by 25 publications

(22 citation statements)

References 34 publications

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“…The new compounds (2, 3 and 4) were formulated based on the elemental analysis, FTIR and NMR ( 1 H, 13 C, DEPT, 2D). Characteristic camphor (ν (CO) ca.…”

Section: Resultsmentioning

confidence: 99%

“…In some cases, solutions obtained upon separation of the complexes by filtration were exposed to air. NMR spectra ( 1 H, 13 C, DEPT, HSQC and HMBC) were obtained from D 2 O or DMSO-d 6 solutions using Bruker Avance II + (300 or 400 MHz) spectrometers. CuCl was synthesized from CuCl 2 by reduction with sodium sulphite.…”

Section: Methodsmentioning

confidence: 99%

“…CuCl 2 (0.12 g, 0.87 mmol) and compound 3 (0.70 g, 1.74 mmol) were mixed and stirred under vacuum for 1 2 h in a Schlenk. Elemental analysis (%) for CuClC 11 A progressive disappearance, during spectra acquisition (MeOH-d 4 ) of the hydrogen atom at position 3, due to deuteration and the broadening of atom C11 (see eqn (3) for labeling) precluding detection by 13 [{CuCl(OC 10 H 15 COOH)}] (X). Alternative procedure: Phenylalanine (0.28 g, 1.7 mmol) and CuCl 2 (0.10 g, 0.77 mmol) were dissolved in deoxygenated water (2 mL) and stirred for 1 1 2 [CuCl(OC 10 H 15 COOLi)]·THF (V·THF).…”

Section: Methodsmentioning

confidence: 99%

“…Besides their apparently similar formula, the compounds have considerably distinct solubility (lower for V) and spectroscopic properties, namely, the IR stretching frequencies (ν COO : 1623 cm −1 (V); 1580 cm −1 (X)) as well as the 13 XPS X-ray photoelectron spectroscopy (XPS) was used to ascertain the composition of selected compounds (II, III and VI) focusing on unraveling the oxidation state of the metal atom. The higher acidity of CuCl solutions conceivably is responsible for Li/H exchange and isolation of X.…”

Section: Reactions Of Lithium 3-camphor Carboximides With Cuclmentioning

confidence: 99%

See 3 more Smart Citations

Oxygen activation by copper camphor complexes

Roseiro

Adão

Galvão

et al. 2015

Inorg. Chem. Front.

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“…The new compounds (2, 3 and 4) were formulated based on the elemental analysis, FTIR and NMR ( 1 H, 13 C, DEPT, 2D). Characteristic camphor (ν (CO) ca.…”

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Reactions Of Lithium 3-camphor Carboximides With Cuclmentioning

confidence: 99%

See 2 more Smart Citations

Oxygen activation by copper camphor complexes

Roseiro

Adão

Galvão

et al. 2015

Inorg. Chem. Front.

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“…18,19 In the past few decades, dinuclear complexes have attracted considerable attention as a result of their chemical and biological reactivity. 44 Again, significant cytotoxic activity and interaction with calf thymus DNA were detected with Cu(II) and Zn(II) complexes of a Schiff base obtained by the condensation reaction of 4-aminoantipyrine with benzaldehyde and Val. 20 Recently, the synthesis and structural characterization of a new rhodium complex containing N-methyl-Dphenylalaninate (NMfO À ) as a chiral ligand have been performed.…”

Section: Introductionmentioning

confidence: 99%

Metal complexes of amino acids and peptides

Farkas¹,

Sóvágó²

2014

Amino Acids, Peptides and Proteins

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DNA/BSA binding interactions and VHPO mimicking potential of vanadium(IV) complexes: Synthesis, structural characterization and DFT studies

Neelakantan

Balakrishnan

Selvarani

et al. 2017

Applied Organom Chemis

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Vanadium(IV) Schiff base complexes (VOL1‐VOL3) were synthesized and characterized by elemental analysis, various spectral methods and single crystal XRD studies. Structural analysis of VOL2 reveals that the central vanadium ion in the complex is six coordinate with distorted octahedral geometry. Density functional theory (DFT) and time dependent (TD‐DFT) studies were used to understand the electronic transitions observed in the complexes in UV–Vis spectra. The electrochemical behavior of the complexes was investigated in acetonitrile medium exhibit quasi‐reversible one electron transfer. The DNA and BSA protein binding interaction of vanadium complexes has been explored by UV–Vis and fluorescence spectral methods and viscosity measurements reveal that the complexes interact with CT‐DNA through intercalation mode and follows the order VOL1 < VOL3 < VOL2. The complexes exhibit binding interactions with BSA protein. The complexes act as chemical nuclease and cleave DNA in the presence of H2O2. The 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) assay was used to evaluate the radical scavenging activity demonstrate the antioxidant property of the complexes. The antimicrobial activity was screened for several microorganisms, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli. The mimicking of vanadium haloperoxidase was investigated by the bromination of the organic substrate phenol red by vanadium complexes in the presence of bromide and H2O2.

show abstract

A systematic investigation on biological activities of a novel double zwitterionic Schiff base Cu(II) complex

Cited by 25 publications

References 34 publications

Oxygen activation by copper camphor complexes

Oxygen activation by copper camphor complexes

Metal complexes of amino acids and peptides

DNA/BSA binding interactions and VHPO mimicking potential of vanadium(IV) complexes: Synthesis, structural characterization and DFT studies

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