During running-in period, the friction coefficient and roughness profile of contacting elements experience drastic changes as a result of asperities deformation and wear. These transient changes affect the steady-state performance of mechanical elements such as gears, cam followers, and bearings. An experimental study on the effect of running-in operating conditions on the properties of a tribosystem is conducted using a pin-on-disk test rig. Curve-fit relationships are developed based on the experimental data to relate running-in duration, friction coefficient, and running-in weight loss to load, speed, and surface roughness. A model to predict the steady-state friction coefficient in the lubricated contact of pin and disk is developed based on the load-sharing concept.