A systematic review and meta-analysis of outcomes following unicompartmental knee arthroplasty versus total knee arthroplasty for unicondylar knee osteoarthritis

Abstract

Review question / Objective: To conduct a systematic review and meta-analysis of randomized controlled trials comparing outcomes following unicompartmental knee arthroplasty versus total knee arthroplasty for patients with unicondylar knee osteoarthritis. Condition being studied: Knee osteoarthritis is a common disease in elderly population and its treatment strategies consist of non-operative treatment and surgery. Arthroplasty is a main surgery for this condition, while the optimal selection between unicompartmental knee arthroplasty and total knee arthroplasty remains debatable. We aim to collect RCTs comparing these two techniques in treatment of knee osteoarthritis and make a meta-analysis in order to provide high level of evidence for future decision-making for this issue.