A systematic review and meta-analysis of the efficacy of ketamine and esketamine on suicidal ideation in treatment-resistant depression

Wang, Ya-Ting; Wang, Xiao-Le; Lei, Lan; Guo, Zhen-Yu; Kan, Fei-Fei; Hu, Die; Gai, Cong; Zhang, Yi

doi:10.1007/s00228-023-03605-1

Eur J Clin Pharmacol

2023

DOI: 10.1007/s00228-023-03605-1

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A systematic review and meta-analysis of the efficacy of ketamine and esketamine on suicidal ideation in treatment-resistant depression

Ya-Ting Wang,

Xiao-Le Wang,

Lan Lei

et al.

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Cited by 4 publications

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Parkin, a Parkinson's disease-associated protein, mediates the mitophagy that plays a vital role in the pathophysiology of major depressive disorder

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Parkin, a Parkinson's disease-associated protein, mediates the mitophagy that plays a vital role in the pathophysiology of major depressive disorder

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Microglia stimulation produces antidepressant-like effects in a mouse depression model induced by adolescent chronic unpredictable stress

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Autism, youth suicide, and psychedelics: A review of the 21st century evidence

Chen,

Su,

Hsu

et al. 2024

Journal of the Chinese Medical Association

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The concurrent rise in the prevalence of autism and youth suicide has drawn public health and professional attention. The renaissance of psychedelics in psychiatry occurred in the early 21st century and may suggest a hope for the therapeutic effect of psychedelics in autism and suicide. The psychedelics' molecular entities are the compounds that modulate the serotoninergic and glutamatergic systems, which play a crucial role in the pathomechanisms underlying autism and suicide. This systematic review comprehensively discussed the prevalence trends of autism and youth suicide globally and in Taiwan and discussed an association between autism and suicidality based on the 21st century clinical and preclinical literature. Furthermore, this review proposed a possible neurobiological connection between autism, suicide, and psychedelics. Finally, this review discussed the potential therapeutic applications of psychedelics in autism and youth suicide.

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A systematic review and meta-analysis of the efficacy of ketamine and esketamine on suicidal ideation in treatment-resistant depression

Cited by 4 publications

References 50 publications

Parkin, a Parkinson's disease-associated protein, mediates the mitophagy that plays a vital role in the pathophysiology of major depressive disorder

Parkin, a Parkinson's disease-associated protein, mediates the mitophagy that plays a vital role in the pathophysiology of major depressive disorder

Microglia stimulation produces antidepressant-like effects in a mouse depression model induced by adolescent chronic unpredictable stress

Autism, youth suicide, and psychedelics: A review of the 21st century evidence

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