A Systematic Review of Implementation of Established Recommended Secondary Prevention Measures in Patients with PAOD

Flu, Hans C.; Tamsma, Jouke T.; Lindeman, J.; Hamming, Jaap F.; Lardenoye, J.H.P.

doi:10.1016/j.ejvs.2009.09.027

Cited by 55 publications

(25 citation statements)

References 72 publications

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“…For cerebral ischemia and PAD, CVRM is suboptimal across countries and regions [6][7][8][9] and it is implemented less frequently than for CAD 10,11 . There are no previous studies on CVRM in CAS but in view of the systematic under-treatment of patients with other forms of non-coronary CVD, it is likely that our findings are not unique.…”

Section: Discussionmentioning

confidence: 99%

High-grade carotid artery stenosis: A forgotten area in cardiovascular risk management

Good

Länne

Wilhelm

et al. 2016

Eur J Prev Cardiolog

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Section: Discussionmentioning

confidence: 99%

High-grade carotid artery stenosis: A forgotten area in cardiovascular risk management

Good

Länne

Wilhelm

et al. 2016

Eur J Prev Cardiolog

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“…Secondary prevention with an antiplatelet drug and a statin can reduce the risk of cardiovascular events in this specific high-risk population 31 . Secondary prevention as given in the included RCTs reflected changing insights over a long time, and varied widely.…”

Section: Secondary Prevention (Co-interventions)mentioning

confidence: 99%

Systematic review of exercise training or percutaneous transluminal angioplasty for intermittent claudication

Frans

Bipat

Reekers

et al. 2012

Journal of British Surgery

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“…Therefore, smoking cessation and therapy for diabetes are strongly recommended for patients with PAD. Lipid-lowering agents, antihypertensive drugs, and anti-platelet drugs are used for patients with PAD 1, 2, 6–8) . However, limited information is available on whether the modification of other atherosclerotic risk factors including obesity, hyperuricemia, and renal dysfunction is effective for preventing the progression of PAD and other cardiovascular complications.…”

Section: Introductionmentioning

confidence: 99%

Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment

Sotoda

Hirooka

Orita

et al. 2017

J Atheroscler Thromb

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Aim: We investigated the relationships of serum uric acid levels with the progression of atherosclerosis in patients with peripheral arterial disease (PAD) after treatment.Methods: Subjects were male patients diagnosed with PAD. Atherosclerosis at the common carotid artery was evaluated based on its intima-media thickness (IMT). Leg arterial flow was evaluated by measuring ankle-brachial index (ABI) and exercise-induced decrease in ABI.Results: Among various risk factors including age, blood pressure, adiposity, estimated glomerular filtration rate, and blood lipid, blood glucose, uric acid, fibrinogen and C-reactive protein levels, only uric acid levels showed significant correlations with ABI [Pearson's correlation coefficient, −0.292 (p < 0.01)] and leg exercise-induced decrease in ABI [Pearson's correlation coefficient, 0.236 (p < 0.05)]. However, there was no significant correlation between uric acid levels and maximum or mean IMT. Odds ratios of subjects with the 3rd tertile versus subjects with the 1st tertile for uric acid levels were significantly higher than the reference level of 1.00 for low ABI [4.44 (95% confidence interval, 1.45–13.65, p < 0.01)] and for high % decrease in ABI after exercise [4.31 (95% confidence interval, 1.34–13.82, p < 0.05)]. The associations of uric acid levels with the indicators of leg ischemia were also found after adjustment for age, history of revascularization therapy, diabetes, smoking, alcohol consumption, body mass index, triglyceride levels, and renal function.Conclusion: Uric acid levels are associated with the degree of leg ischemia in patients with PAD. Further interventional studies are needed to determine whether the correction of uric acid levels is effective in preventing the progression of PAD.

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A Systematic Review of Implementation of Established Recommended Secondary Prevention Measures in Patients with PAOD

Abstract: The majority of patients suffering from PAOD do not receive the entire approach of SP measures as suggested by the current guidelines. To our knowledge, the cause of this undertreatment is multifactorial: patient, physician or health-care-related.

Cited by 55 publications

References 72 publications

High-grade carotid artery stenosis: A forgotten area in cardiovascular risk management

High-grade carotid artery stenosis: A forgotten area in cardiovascular risk management

Systematic review of exercise training or percutaneous transluminal angioplasty for intermittent claudication

Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment

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