2023
DOI: 10.1101/2023.08.29.23294656
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A Systematic Review on the Effect of Diabetes Mellitus on the Pharmacokinetics of Tuberculosis Drugs

Muge Cevik,
Ann Sturdy,
Alberto Enrico Maraolo
et al.

Abstract: While pharmacokinetics (PK) of many drugs is known to be altered in individuals with diabetes mellitus (DM), the effects of DM on the PK of anti-tuberculosis (TB) drugs remains poorly understood.We performed a systematic review through searches of major databases from 1946 to 6 July 2023. The literature search identified 4173 potentially relevant articles. After reviewing the eligibility criteria, 21 articles were included that assessed the PK of anti-TB drugs among patients with DM.Most articles focused on fi… Show more

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