A Systematic Review Over the Incidence of Colorectal Cancer in Iran

Abstract

Context:Colorectal cancer (CRC) is the third most prevalent cancer worldwide which is less common in the Middle East. It is also the second leading cause of cancer-related mortality and represents a major public health problem in developed countries. Objectives: The present review aimed to explore the differences among the reports on number and age standardized incidences of CRC in both sexes in different areas of Iran to find the incidence trend of this cancer. Data Sources: All the published reports citing the incidence of CRC in Iran were collected by conducting a literature search in international databases. Study Selection: English articles were included where there was a clear definition of the population of patients under study and where the criteria for diagnosing CRC were well described. Data Extraction: One author read each paper and extracted several studies and then the studies suitable for inclusion were reported in three categories. Results: We identified 181 independent studies dating back to 2003; 168 full text articles were assessed for eligibility. However, 136 full text articles were excluded due to different reasons. Finally, 26 studies were suitable for inclusion in the analysis. The highest and lowest (age standardized rates) ASRs were respectively 3.4 and 2.6 in males and 11.42 and 10.56 in females. Time showed a slightly increasing trend in recent years. Conclusions: Although Iran was expected to have a low incidence rate of CRC, recent studies revealed a slightly increasing trend for the incidence rate of CRC. This finding shows the necessity to consider CRC screening as an important issue in health policy priorities.

Colorectal cancer incidence and clinicopathological features in northern Tunisia 2007–2009

“…Incidence rates were 10.5/100,000 (12 in men and nine in women) in Morocco (2006-2008 registry) [24] and 11/100,000 (8.7 in men and 13.4 in women) [25] [28] and Kuwait (12.7/100,000 [13.6-11.8]) [29] show almost similar incidence to our results. In contrast, incidence observed in this study were higher than those recorded in Iran in 2009 (8.5/100,000 [11.3-5.8]) [30] and in Egypt (5.4/100,000 [6-4.9]) [31].…”

Survival Analysis of Colorectal Cancer Patients Using Exponentiated Weibull Distribution

“…It is also the fifth and third most frequent cancer among Iranian men and women, respectively (7). Unfortunately, the prevalence of colorectal cancer has been on the rise in Iran (8).…”

A Review of the Incidence of Colorectal Cancer in the Middle East

“…As shown in graph No.1, this risk was half of that of Jordan and Arab Palestinians. According to a systematic review, the risk of CRC in Iran, especially in northern and western parts, showed a mild rise during the recent 2 decades, while several studies reported lower incidence rates from southern and eastern parts of this country (19). The southern countries of the Middle East, Oman and Yemen, showed the least risk of CRC, in both the Middle East and worldwide.…”