A Systemic Review on the Synthesis, Characterization, and Applications of Palladium Nanoparticles in Biomedicine

MubarakAli, D.; Kim, Hoekun; Venkatesh, Perumalsamy Sundara; Kim, Jung-Wan; Lee, Sang-Yul

doi:10.1007/s12010-022-03840-9

Cited by 31 publications

(6 citation statements)

References 80 publications

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“…To carry out the study, a systematic review of the literature was used as a strategy to identify both Systematic reviews of the literature are the most widely used tool (MubarakAli et al, 2022;Heo et al, 2022) to identify, evaluate and interpret the data that we want to study, available in a given period of time and a field of research specific.…”

Section: Design and Planningmentioning

confidence: 99%

Untitled

2023

EJA

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Segmentation anomalies of the spine transformations are relatively common in humans, mainly in adjacent regions. Its aetiology is multifactorial, a combination of genetic, environmental, and epigenetic interaction. A sample of 50 adult individuals of both sexes from two different sites and chronologies of the current Argentine territory was examined. This work proposes a new approach to analyse segmentation anomalies, considering the taphonomic characteristics of the spine, together with the most common occasional contour shifts of such anomalies. Likewise, a bibliographic review was conducted to compile the knowledge achieved to date on this topic. The results showed different patterns of expression of segmentation anomalies among the analysed samples, with the lumbosacral transformations being the most prevalent. The similarities and disparities observed between Southern Patagonian samples and Inuit populations suggest that cold, as an environmental factor, could play an important role in the phenotypic plasticity of human populations. Similarly, hypoxia could influence the sample from Pukará de Tilcara. Due to the scarce existing methodological standardization for addressing segmentation anomalies, a systematization of the methods used to analyse segmentation anomalies is recommended; our approach is a proposal for this purpose.

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Section: Design and Planningmentioning

confidence: 99%

Untitled

2023

EJA

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“…Palladium nanoparticles (Pd) have attracted attention in industry and research owing to their versatility and catalytic efficiency. High surface area and reactivity make them useful in many applications ranging from material science and healthcare to energy and environmental-related technologies [11,12]. In addition, Pd nanoparticles have potential biomedical applications, including drug delivery systems and photothermal therapy for cancer treatment [13].…”

Section: Introductionmentioning

confidence: 99%

Gelatin-Coated TiO2/Pd Hybrid: A Potentially Useful Nanomaterial to Enhance Antibacterial and Anticancer Properties

Anbu,

Rethinasabapathy,

Sathiyaseelan

et al. 2024

IJMS

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Hybrid nanomaterials have attracted considerable interest in biomedicine because of their fascinating characteristics and wide range of applications in targeted drug delivery, antibacterial activity, and cancer treatment. This study developed a gelatin-coated Titanium oxide/palladium (TiO2/Pd) hybrid nanomaterial to enhance the antibacterial and anticancer capabilities. Morphological and structural analyses were conducted to characterize the synthesized hybrid nanomaterial. The surface texture of the hybrid nanomaterials was examined by high-resolution transmission electron microscopy (HR-TEM) and field-emission scanning electron microscopy (FE-SEM). The FE-SEM image revealed the bulk of the spherically shaped particles and the aggregated tiny granules. Energy dispersive X-ray spectroscopy (EDS) revealed Ti, Pd, C, and O. X-ray diffraction (XRD) revealed the gelatin-coated TiO2/Pd to be in the anatase form. Fourier transform infrared spectroscopy examined the interactions among the gelatin-coated TiO2/Pd nanoparticles. The gelatin-coated TiO2/Pd nanomaterials exhibited high antibacterial activity against Escherichia coli (22 mm) and Bacillus subtilis (17 mm) compared to individual nanoparticles, confirming the synergistic effect. More importantly, the gelatin-coated TiO2/Pd hybrid nanomaterial exhibited remarkable cytotoxic effects on A549 lung cancer cells which shows a linear increase with the concentration of the nanomaterial. The hybrid nanomaterials displayed higher toxicity to cancer cells than the nanoparticles alone. Furthermore, the cytotoxic activity against human cancer cells was verified by the generation of reactive oxygen species and nuclear damage. Therefore, gelatin-coated TiO2/Pd nanomaterials have potential uses in treating cancer and bacterial infections.

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“…PdNP have shown a significant potential for the development of nanomedicine with characteristic antimicrobial, wound healing, antioxidant, and anticancer properties. Biogenic PdNP are biocompatible, widely distributed, and generally preserve the anticancer properties of the plant extracts and microorganisms such as bacteria, algae, fungi, and viruses used for the synthesis [ 23 ]. Moreover, PdNP’s intrinsic anticancer properties include DNA and protein damage and inactivation [ 24 , 25 ], the leakage of lactate dehydrogenase [ 26 ], and the production of free radicals of both ROS and reactive nitrogen species (RNS) that cause lipid degradation [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

Green Nanoformulations of Polyvinylpyrrolidone-Capped Metal Nanoparticles: A Study at the Hybrid Interface with Biomimetic Cell Membranes and In Vitro Cell Models

Foti,

Calì,

Petralia

et al. 2023

Nanomaterials

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Noble metal nanoparticles (NP) with intrinsic antiangiogenic, antibacterial, and anti-inflammatory properties have great potential as potent chemotherapeutics, due to their unique features, including plasmonic properties for application in photothermal therapy, and their capability to slow down the migration/invasion speed of cancer cells and then suppress metastasis. In this work, gold (Au), silver (Ag), and palladium (Pd) NP were synthesized by a green redox chemistry method with the reduction of the metal salt precursor with glucose in the presence of polyvinylpyrrolidone (PVP) as stabilizing and capping agent. The physicochemical properties of the PVP-capped NP were investigated by UV-visible (UV-vis) and attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopies, dynamic light scattering (DLS), and atomic force microscopy (AFM), to scrutinize the optical features and the interface between the metal surface and the capping polymer, the hydrodynamic size, and the morphology, respectively. Biophysical studies with model cell membranes were carried out by using laser scanning confocal microscopy (LSM) with fluorescence recovery after photobleaching (FRAP) and fluorescence resonance energy transfer (FRET) techniques. To this purpose, artificial cell membranes of supported lipid bilayers (SLBs) made with 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (POPC) dye-labeled with 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD, FRET donor) and/or lissamine rhodamine B sulfonyl (Rh, FRET acceptor) were prepared. Proof-of-work in vitro cellular experiments were carried out with prostate cancer cells (PC-3 line) in terms of cytotoxicity, cell migration (wound scratch assay), NP cellular uptake, and cytoskeleton actin perturbation.

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A Systemic Review on the Synthesis, Characterization, and Applications of Palladium Nanoparticles in Biomedicine

Cited by 31 publications

References 80 publications

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Gelatin-Coated TiO2/Pd Hybrid: A Potentially Useful Nanomaterial to Enhance Antibacterial and Anticancer Properties

Green Nanoformulations of Polyvinylpyrrolidone-Capped Metal Nanoparticles: A Study at the Hybrid Interface with Biomimetic Cell Membranes and In Vitro Cell Models

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